ArticleIndian journal of clinical biochemistry : IJCB2013
The Uncertainty of the eGFR.
Article in Indian journal of clinical biochemistry : IJCB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biological variation and reference change value of the estimated glomerular filtration rate in humans: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Are accreditation standards fit for measurement uncertainty in clinical laboratories? An analysis of Saudi Arabia's accreditation.Frontiers in medicine · 2026Article
- Repeatability, Reproducibility, and Observer Variability of Cortical T1 Mapping for Renal Tissue Characterization.Journal of magnetic resonance imaging : JMRI · 2025Article
- Key Considerations for Frail Patients Undergoing Hip Fracture Surgery.Clinics and practice · 2024Review
- Current Challenges and Future Perspectives of Renal Tubular Dysfunction in Diabetic Kidney Disease.Frontiers in endocrinology · 2021Review
- Potential for Novel Biomarkers in Diabetes-Associated Chronic Kidney Disease: Epigenome, Metabolome, and Gut Microbiome.Biomedicines · 2020Review
- Uncertainty in measurement: A review of the procedures for determining uncertainty in measurement and its use in deriving the biological variation of the estimated glomerular filtration rate.Practical laboratory medicine · 2018Review
- Creatinine Assay Attainment of Analytical Performance Goals Following Implementation of IDMS Standardization: Further Improvements Required.Canadian journal of kidney health and disease · 2017Article
- A Risk Assessment of the Jaffe vs Enzymatic Method for Creatinine Measurement in an Outpatient Population.PloS one · 2015Article
- Incomplete reversibility of estimated glomerular filtration rate decline following tenofovir disoproxil fumarate exposure.The Journal of infectious diseases · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The estimated glomerular filtration rate (eGFR) is a parameter derived from the serum creatinine, patient age and gender and is used to ascertain renal function. It is subject to variation because of the analytical error of the creatinine measurement and biological variation. The widespread use of the eGFR to classify renal disease has led to the identification of more patients with marginal chronic kidney disease but because of the uncertainty of the eGFR it has also led to over-diagnosis of some kidney disease. There is a well described age relation with eGFR.The uncertainty of the eGFR at the critical decision level of 60 mL/min/1.73 m(2) is calculated to be 11. Caution needs to be exercised when interpreting an eGFR between 49 and 71 mL/min/1.73 m(2).
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Registered trials
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