ArticleIndian journal of microbiology2014
Identification and Characterization of an Invasion Antigen B Gene from the Oral Pathogen Campylobacter rectus.
Article in Indian journal of microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Comparative genomic analysis ofFrontiers in microbiology · 2023Article
- Wiskott-Aldrich syndrome: Oral findings and microbiota in children and review of the literature.Clinical and experimental dental research · 2022Review
- Identification and Characterization of a Putative Chemotaxis Protein, CheY, from the Oral PathogenThe Internet journal of microbiologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
The oral bacterium, Campylobacter rectus, is an etiological agent of periodontitis. The virulence genes of C. rectus are largely unknown. The aim of this study was to query C. rectus for the presence of an invasion antigen B (ciaB) gene, which is needed for cell invasion by the related species Campylobacter jejuni. PCR and PCR-walking identified a ciaB from C. rectus. In silico analyses of C. rectus 314 ciaB (Cr-ciaB) revealed an ORF of 1,830 base pairs. The Cr-CiaB protein shared significant sequence identity (BLASTx and phylogeny) with CiaB from related campylobacters. Cr-CiaB is predicted to lack membrane helices, signal peptides, and localizes to the cytoplasm; which are consistent with CiaB proteins. Expression of Cr-ciaB was confirmed with RT-PCR; and potential ciaB genes were detected in eight additional strains of C. rectus. Cr-ciaB is the first CiaB identified from the oral campylobacters.
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