ArticleMolecular biology reports1987
A hsp70-related gene is constitutively highly expressed in testis of rat and mouse.
Article in Molecular biology reports, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 39 citations in OpenAlex.
- Expression, function, and regulation of the testis-enriched heat shock HSPA2 gene in rodents and humans.Cell stress & chaperones · 2015Review
- Identification of a testis-enriched heat shock protein and fourteen members of Hsp70 family in the swamp eel.PloS one · 2013Article
- The expression pattern of the 70-kDa heat shock protein Hspa2 in mouse tissues.Histochemistry and cell biology · 2009Article
- Location of promoter elements necessary and sufficient to direct testis-specific expression of the Hst70/Hsp70.2 gene.The Biochemical journal · 2004Article
- Structure of the 5' region of the Hst70 gene transcription unit: presence of an intron and multiple transcription initiation sites.The Biochemical journal · 2001Article
- Stage-specific localization of cytoskeletal actin mRNA in murine seminiferous tubules and intestinal epithelia as demonstrated by in-situ hybridization.Cell and tissue research · 1989Article
- A 14 bp promoter element directs the testis specificity of the Drosophila beta 2 tubulin gene.The EMBO journal · 1989Article
- Expression of a testis-specific hsp70 gene-related RNA in defined stages of rat seminiferous epithelium.The Journal of cell biology · 1988Article
- Expression of heat shock proteins by isolated mouse spermatogenic cells.Molecular and cellular biology · 1988Article
- A novel hsp70-like protein (P70) is present in mouse spermatogenic cells.Molecular and cellular biology · 1988Article
- Isolation of major heat shock protein (hsp70) gene-related sequences from rat genome.Molecular biology reports · 1988Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expression pattern of major heat shock related genes (hsp70 gene family) in various organs of mouse and rat was investigated using Northern blot analysis. Heat shock gene related transcripts were detected in total RNA by hybridization with cloned mouse hsp70 gene sequences. Cells of various organs of intact mouse and rat constitutively synthesize a 2.2 kb and a 2.5 kb RNA. Exceptionally high levels of the 2.5 kb RNA, 50-250 fold higher than in other tissues are found in testis of both rodents. The 2.5 kb RNA hybridizes strongly to an extended region of mouse hsp70 gene; it also hybridizes poorly to the Drosophila hsp70 gene. The data suggest that the 2.5 kb RNA is transcribed from a hsp70-related gene in mouse and rat.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.