Evidence map›Paper›PMID 24424074›Full record

Trial reportEuropean journal of clinical nutrition2014

Acute effects of pistachio consumption on glucose and insulin, satiety hormones and endothelial function in the metabolic syndrome.

C W C Kendall, S G West, L S Augustin, A Esfahani, E Vidgen, B Bashyam, K A Sauder, J Campbell, L Chiavaroli, A L Jenkins and 1 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Effects of Hazelnut Consumption on Cardiometabolic Risk Factors and Acceptance: A Systematic Review.International journal of environmental research and public health · 2022
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  12. Believe It or 'Nutrients · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

C W C Kendall1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada [3] College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada.
S G West1] Biobehavioral Health, Pennsylvania State University, University Park, PA, USA [2] Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.
L S Augustin1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
A EsfahaniSchool of Medicine, New York Medical College, Valhalla, NY, USA.
E Vidgen1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
B Bashyam1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
K A SauderBiobehavioral Health, Pennsylvania State University, University Park, PA, USA.
J CampbellGlycemic Index Laboratories, Toronto, ON, Canada.
L Chiavaroli1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
A L Jenkins1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Glycemic Index Laboratories, Toronto, ON, Canada.
D J Jenkins1] Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada [2] Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada [3] Department of Medicine, Division of Endocrinology and Metabolism, St Michael's Hospital, Toronto, ON, Canada.
St. Michael's Hospital · CAUniversity of Toronto · CAPennsylvania State University · USGlycemic Index Laboratories · CANew York Medical College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveNut consumption has been found to decrease risk of coronary heart disease and diabetes and to promote healthy body weights possibly related to their favorable macronutrient profile. We therefore assessed the effect of pistachios on postprandial glucose and insulin levels, gut hormones related to satiety and endothelial function. SUBJECTS/

methodsIn this randomized crossover study, 20 subjects with metabolic syndrome consumed five study meals over 5-10 weeks. The meals differed in fat type and quantity, but were matched according to available carbohydrates (CHOs). Three meals had 50 g available CHO: white bread (WB50g), white bread, butter and cheese (WB+B+Ch) and white bread and pistachios (WB+P). Two meals had 12 g available CHO: white bread (WB12g) and pistachios (P).

resultsWithin each group of available CHO meals, postprandial glucose levels were the highest following the white bread-only meals, and glucose response was significantly attenuated when butter and cheese or pistachios were consumed (P<0.05). Postprandial insulin levels were highest after the WB+B+Ch meal (P<0.05), but did not differ between the white bread-only and pistachio meals. Both endothelial function (reactive hyperemia index) and arterial stiffness (augmentation index) significantly increased after the white bread-only meals compared with the WB+B+Ch meal (all P<0.05). Insulin secretagogue levels were higher when butter and cheese or pistachios were consumed than when white bread only was consumed (P<0.05).

conclusionsCompared with white bread, pistachio consumption reduced postprandial glycemia, increased glucagon-like-peptide levels and may have insulin-sparing properties. These effects could be beneficial for individuals with diabetes and metabolic syndrome.

Indexed as

AdultAgedBlood GlucoseBreadCross-Over StudiesEndotheliumFemaleHumansInsulinMaleMealsMetabolic SyndromeMiddle AgedNutsPistaciaPostprandial PeriodBlood GlucoseInsulin

Identifiers

PMID24424074
OpenAlexW2088768230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.