ArticleJournal of applied clinical medical physics2014
Clinical introduction of Monte Carlo treatment planning for lung stereotactic body radiotherapy.
Article in Journal of applied clinical medical physics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Effects of maximum dose on local control after stereotactic body radiotherapy for oligometastatic tumors of colorectal cancer.PloS one · 2025Article
- A comprehensive evaluation of advanced dose calculation algorithms for brain stereotactic radiosurgery.Journal of applied clinical medical physics · 2023Article
- Stereotactic ablative body radiotherapy with a central high dose using CyberKnife for metastatic lung tumors.BMC cancer · 2023Article
- Effectiveness of robust optimization in volumetric modulated arc therapy using 6 and 10 MV flattening filter-free beam therapy planning for lung stereotactic body radiation therapy with a breath-hold technique.Journal of radiation research · 2020Article
- Tolerance levels of mass density for CT number calibration in photon radiation therapy.Journal of applied clinical medical physics · 2019Article
- Technical and dosimetric implications of respiratory induced density variations in a heterogeneous lung phantom.Radiation oncology (London, England) · 2018Article
- Does intensity modulation increase target dose calculation errors of conventional algorithms for lung SBRT?Journal of applied clinical medical physics · 2018Article
- A comprehensive dosimetric study on switching from a Type-B to a Type-C dose algorithm for modern lung SBRT.Radiation oncology (London, England) · 2017Article
- Effect of the normalized prescription isodose line on the magnitude of Monte Carlo vs. pencil beam target dose differences for lung stereotactic body radiotherapy.Journal of applied clinical medical physics · 2016Article
- Target dose conversion modeling from pencil beam (PB) to Monte Carlo (MC) for lung SBRT.Radiation oncology (London, England) · 2016Article
- Assessment of Monte Carlo algorithm for compliance with RTOG 0915 dosimetric criteria in peripheral lung cancer patients treated with stereotactic body radiotherapy.Journal of applied clinical medical physics · 2016Article
- Combination effects of tissue heterogeneity and geometric targeting error in stereotactic body radiotherapy for lung cancer using CyberKnife.Journal of applied clinical medical physics · 2015Article
- Stereotactic body radiotherapy for Stage I lung cancer with chronic obstructive pulmonary disease: special reference to survival and radiation-induced pneumonitis.Journal of radiation research · 2015Article
- Differences in rates of radiation-induced true and false rib fractures after stereotactic body radiation therapy for Stage I primary lung cancer.Journal of radiation research · 2015Article
- Technical Note: Dosimetric evaluation of Monte Carlo algorithm in iPlan for stereotactic ablative body radiotherapy (SABR) for lung cancer patients using RTOG 0813 parameters.Journal of applied clinical medical physics · 2015Article
- Dose Prescription Methods in Stereotactic Body Radiotherapy for Small Peripheral Lung Tumors: Approaches Based on the Gross Tumor Volume Are Superior to Prescribing a Dose That Covers 95% of the Planning Target Volume.Technology in cancer research & treatmentArticle
- An Approach in Radiation Therapy Treatment Planning: A Fast, GPU-Based Monte Carlo Method.Journal of medical signals and sensorsArticle
- Local control rates in stereotactic body radiotherapy (SBRT) of lung metastases associated with the biologically effective dose.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
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7 authors.
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Abstract
The purpose of this study was to investigate the impact of Monte Carlo (MC) calculations and optimized dose definitions in stereotactic body radiotherapy (SBRT) for lung cancer patients. We used a retrospective patient review and basic virtual phantom to determine dose prescriptions. Fifty-three patients underwent SBRT. A basic virtual phantom had a gross tumor volume (GTV) of 10.0 mm with equivalent water density of 1.0 g/cm3, which was surrounded by equivalent lung surrounding the GTV of 0.25 g/cm3. D95 of the planning target volume (PTV) and D99 of the GTV were evaluated with different GTV sizes (5.0 to 30.0 mm) and different lung densities (0.05 to 0.45 g/cm3). Prescribed dose was defined as 95% of the PTV should receive 100% of the dose (48 Gy/4 fractions) using pencil beam (PB) calculation and recalculated using MC calculation. In the patient study, average doses to the D95 of the PTV and D99 of the GTV using the MC calculation plan were 19.9% and 10.2% lower than those by the PB calculation plan, respectively. In the phantom study, decreased doses to the D95 of the PTV and D99 of the GTV using the MC calculation plan were accompanied with changes GTV size from 30.0to 5.0 mm, which was decreased from 8.4% to 19.6% for the PTV and from 17.4%to 27.5% for the GTV. Similar results were seen with changes in lung density from 0.45 to 0.05 g/cm3, with doses to the D95 of the PTV and D99 of the GTV were decreased from 12.8% to 59.0% and from 7.6% to 44.8%, respectively. The decrease in dose to the PTV with MC calculation was strongly dependent on lung density. We suggest that dose definition to the GTV for lung cancer SBRT be optimized using MC calculation. Our current clinical protocol for lung SBRT is based on a prescribed dose of 44 Gy in 4 fractions to the GTV using MC calculation.
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