ArticleWorld journal of surgical oncology2014
Lower skeletal muscle index and early complications in patients undergoing radical cystectomy for bladder cancer.
Article in World journal of surgical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The impact of preoperative nutritional status on post-surgical complication and mortality rates in patients undergoing radical cystectomy for bladder cancer: a systematic review of the literature.World journal of urology · 2021Pooled it
- A Low Psoas Muscle Index before Treatment Can Predict a Poorer Prognosis in Advanced Bladder Cancer Patients Who Receive Gemcitabine and Nedaplatin Therapy.BioMed research international · 2017Trial
- Review
- Sarcopenia is associated with leukopenia in urothelial carcinoma patients who receive tislelizumab combined with gemcitabine and cisplatin therapy.International journal of clinical oncology · 2024Article
- Evaluation of sarcopenia in patients receiving intravesical Bacillus Calmette-Guérin for non-muscle invasive bladder cancer.Urologic oncology · 2023Article
- Relationships of body composition and adipocytokines with outcomes in metastatic castration-resistant prostate cancer patients receiving docetaxel chemotherapy.Asian journal of andrology · 2023Article
- Sarcopenia as an independent predictor for venous thromboembolism events in bladder cancer patients undergoing radical cystectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Sarcopenia is associated with survival in patients with urothelial carcinoma treated with systemic chemotherapy.International journal of clinical oncology · 2022Article
- The association between sarcopenia and bladder cancer-specific mortality and all-cause mortality after radical cystectomy: A systematic review and meta-analysis.Arab journal of urology · 2021Review
- Impact of Sarcopenia on Functional and Oncological Outcomes After Radical Prostatectomy.Frontiers in surgery · 2020Article
- Sarcopenia as a significant predictive factor of neutropenia and overall survival in urothelial carcinoma patients underwent gemcitabine and cisplatin or carboplatin.International journal of clinical oncology · 2020Article
- Article
- Studying the impact of comorbidity on post radical cystectomy survival: have we come a full circle?Translational andrology and urology · 2019Article
- Sarcopenia is a poor prognostic factor of castration-resistant prostate cancer treated with docetaxel therapy.Prostate international · 2019Article
- Sarcopenia is a reliable predictor of outcomes following radical cystectomy for bladder cancer.Translational andrology and urology · 2018Article
- Changes in Lean Muscle Mass Associated with Neoadjuvant Platinum-Based Chemotherapy in Patients with Muscle Invasive Bladder Cancer.Bladder cancer (Amsterdam, Netherlands) · 2018Article
- Early Complications and Mortality following Radical Cystectomy: Associations with Malnutrition and Obesity.Bladder cancer (Amsterdam, Netherlands) · 2018Article
- Impact of Sarcopenia as a Prognostic Biomarker of Bladder Cancer.International journal of molecular sciences · 2018Review
- Sarcopenia predicts 90-day mortality and postoperative complications after radical cystectomy for bladder cancer.World journal of urology · 2018Article
- Sarcopenia as a comorbidity-independent predictor of survival following radical cystectomy for bladder cancer.Journal of cachexia, sarcopenia and muscle · 2018Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRadical cystectomy (RC) is the standard treatment for patients with muscle-invasive bladder cancer (BC), and it is also a valid option for selected patients with high-risk non-muscle-invasive BC. The purpose of this study was to evaluate the effect on the lower skeletal muscle index (SMI) of short-term postoperative complications of radical cystectomy (RC) in patients with bladder cancer (BC).
methodsA total of 247 patients who received RC for BC and 204 age-matched healthy population-based controls were retrospectively assessed. SMI was measured by preoperative computed tomography scans at the L4 to L5 level. Early complications were graded by Clavien-Dindo classification; severity of grade III or greater was identified as a severe complication. Logistic regression was utilized to determine the relationships between covariables and severe complications.
resultsA total of 125 (50.61%)/19 (7.69%) patients exhibited overall/severe complications during the early postoperative period. SMI was strongly associated with gender (P <0.01), but not age and body mass index (BMI), among patients with BC. Compared with the matched control group, BC patients exhibited lower SMI. The difference was statistically significant in the subgroup of male patients (P = 0.03). In the multivariate analysis, SMI was an independent predictor of developing severe complications. Each 1 cm²/m² increase in SMI was associated with a decrease in the odds of morbidity by 4.8%.
conclusionsA lower SMI is frequently observed in bladder cancer patients undergoing RC and is shown to be strongly associated with early complications following surgery.
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