ReviewJournal of oral & maxillofacial research2012
Head and neck cancer pain: systematic review of prevalence and associated factors.
Review in Journal of oral & maxillofacial research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Prevalence of orofacial and head pain: an umbrella review of systematic reviews.Journal of oral & facial pain and headache · 2024Pooled it
- Risk and Health Factors for Temporomandibular Disorders Following Radiotherapy for Head and Neck Cancer.Journal of oral rehabilitation · 2025Trial
- The Impact of Cancer Treatment On Oral Structures and the Facial Part of the Skull - Implications for Prosthetic Treatment and Oncological Risk.Current oncology reports · 2026Review
- Sex influences on tumor innervation.Biology of sex differences · 2026Article
- Effectiveness of physical therapy techniques for cancer-related pain: a systematic review.Frontiers in rehabilitation sciences · 2026Review
- Cancer-related pain in head and neck cancer survivors: longitudinal findings from the Head and Neck 5000 clinical cohort.Journal of cancer survivorship : research and practice · 2025Article
- A Retrospective Study of Best Supportive Care as Initial Treatment for Oral Squamous Cell Carcinoma.Cureus · 2025Article
- Musculoskeletal Impairments and Dysfunction in Individuals with Head and Neck Cancer Following Surgery with Neck Dissection-A Systematic Review.Life (Basel, Switzerland) · 2025Review
- "Women's experiences of head and neck cancer: an interpretative phenomenological analysis".BMC women's health · 2025Article
- Non-curative care options for patients with advanced-stage head and neck cancer: Current state of the science and future opportunities.Palliative & supportive care · 2025Review
- Bridging the pain gap after cancer surgery - Evaluating the feasibility of transitional pain service to prevent persistent postsurgical pain - A systematic review and meta-analysis.Indian journal of anaesthesia · 2024Article
- Article
- Understanding the role of nerves in head and neck cancers - a review.Oncology reviews · 2024Review
- Improved quality of life in head and neck cancer patients treated with modern arc radiotherapy techniques - A prospective longitudinal analysis.Frontiers in oncology · 2024Article
- Article
- Sociodemographic Differences in Patient-Reported Pain and Pain Management of Patients With Head and Neck Cancer in a Community Oncology Setting.JCO oncology practice · 2023Article
- A pilot study to improve pain phenotyping in head and neck cancer patients.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Psychoneurological Symptoms and Biomarkers of Stress and Inflammation in Newly Diagnosed Head and Neck Cancer Patients: A Network Analysis.Current oncology (Toronto, Ont.) · 2022Article
- Advances in Head and Neck Cancer Pain.Journal of dental research · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPain is a major symptom in patients with cancer; however information on head and neck cancer related pain is limited. The aim of this review was to investigate the prevalence of pain and associated factors among patients with HNC. MATERIAL AND
methodsThe systematic review used search of MEDLINE, EMBASE and CINAHL databases to December 2011. Cancers of the oral mucosa, oropharynx, hypopharynx and larynx were included in this review with pain as main outcome. The review was restricted to full research reports of observational studies published in English. A checklist was used to assess the quality of selected studies.
resultsThere were 82 studies included in the review and most of them (84%) were conducted in the past ten years. Studies were relatively small, with a median of 80 patients (IQR 44, 154). The quality of reporting was variable. Most studies (77%) used self-administered quality of life questionnaires, where pain was a component of the overall scale. Only 33 studies reported pain prevalence in HNC patients (combined estimate from meta-analysis before (57%, 95% CI 43% - 70%) and after (42%, 95% CI 33% - 50%) treatment. Only 49 studies (60%) considered associated factors, mostly tumour- or treatment-related.
conclusionsThe study has shown high levels of pain prevalence and some factors associated with higher levels of pain. There is a need for higher quality studies in a priority area for the care of patients with head and neck cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.