Evidence map›Paper›PMID 24421980›Full record

ArticleJournal of oral & maxillofacial research2011

Granular cell ameloblastoma: an unusual histological subtype report and review of literature.

Nikolaos G Nikitakis, Fotios Tzerbos, Kyriaki Triantafyllou, Christos Papadimas, Alexandra Sklavounou

Open access · diamondAbstract read
In one paragraph

Article in Journal of oral & maxillofacial research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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  6. Odontogenic keratocyst with granular cell changes: A distinctive finding.Journal of oral and maxillofacial pathology : JOMFP
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  8. Granular cell ameloblastoma - A rare entity with recurrence after 48 years.Journal of oral and maxillofacial pathology : JOMFP
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nikolaos G NikitakisDepartment of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens Greece.
Fotios TzerbosDepartment of Oral and Maxillofacial Surgery, School of Dentistry, National and Kapodistrian University of Athens Greece.
Kyriaki TriantafyllouDepartment of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens Greece.
Christos PapadimasDepartment of Oral and Maxillofacial Surgery, School of Dentistry, National and Kapodistrian University of Athens Greece.
Alexandra SklavounouDepartment of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGranular cell ameloblastoma is a rare histological subtype of ameloblastoma accounting for less than 5% of the total. The characteristic microscopic features of granular cells are attributed to the increased presence of lysosomes in the cytoplasm of the tumour cells.

methodsA case of bone expansion in the mandible of 65 year old patient was examined on the basis of the clinical examination, radiographic imaging and microscopic features. A complete surgical removal was performed.

resultsThe radiographic imaging characteristics were consistent with a locally aggressive jaw lesion. Histological examination of the tumour revealed typical features of granular cell ameloblastoma. The specimen margins were free of tumour and the postoperative course was uneventful. No evidence of recurrence was noticed during a 1.5 years follow-up period.

conclusionsThe rarity of the granular cell ameloblastoma subtype and the possibility of confusion with other odontogenic and non-odontogenic lesions with a granular cell component require an understanding of the salient features of this locally aggressive neoplasm. A literature review is provided focusing on emerging molecular parameters in the pathogenesis of these tumours and the differential diagnosis of oral lesions featuring granular cells.

Indexed as

ameloblastomajaw neoplasmslysosomes.odontogenic tumor

Identifiers

PMID24421980
PMCPMC3886069
OpenAlexW2029118100

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.