ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2013
Ten-year review of candidemia in a Canadian tertiary care centre: Predominance of non-albicans Candida species.
Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Nucleic Acid Amplification Tests forPathogens (Basel, Switzerland) · 2026Pooled it
- Candidemia Treatment is Improved by Infectious Disease Consultation: A Population-Based Cohort Study.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024Article
- Article
- Incidence, susceptibility and outcomes of candidemia in adults living in Calgary, Alberta, Canada (2010-2018).BMC infectious diseases · 2023Article
- Article
- Deciphering the epidemiology of invasive candidiasis in the intensive care unit: is it possible?Infection · 2021Review
- Candidemia in pediatric burn patients: Risk factors and outcomes in a retrospective cohort study.Current medical mycology · 2020Article
- Concurrent bloodstream infection withMedical mycology case reports · 2020Article
- An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.PloS one · 2020Article
- Epidemiology, risk factors and outcomes ofEpidemiology and infection · 2019Article
- First report of Candida bracarensis in Mexico: hydrolytic enzymes and antifungal susceptibility pattern.Folia microbiologica · 2018Article
- A Fatal Case of Candida auris and Candida tropicalis Candidemia in Neutropenic Patient.Mycopathologia · 2018Article
- Review
- Oropharyngeal candidiasis in children with lymphohematopoietic malignancies in Mashhad, Iran.Current medical mycology · 2015Article
- Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience.Infection and drug resistance · 2015Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo review the epidemiology and associated risk factors for candidemia at a tertiary care centre, in view of recent reports on the changing epidemiology of bloodstream infection due to Candida species.
methodsBetween January 2000 and December 2009, patients with blood culture samples positive for Candida species were identified using the microbiology laboratory information system. Patient data were collected by retrospective chart review of clinical characteristics including demographic data, underlying medical diagnoses and risk factors.
resultsA total of 266 candidemia episodes were included in the final analysis. Fifty-nine per cent of these episodes occurred in males and 51% were in patients >60 years of age. The most common risk factor for candidemia was previous antibiotic use (85%). The most frequent species was Candida albicans (49%), followed by Candida glabrata (30%). C albicans was the predominant species in all study years with the exception of 2002, in which C glabrata was more frequent. The likelihood of recovering a non-albicans Candida species was found to be significantly associated with previous antifungal therapy (P=0.0004), immunosuppressive therapy (P=0.002), abdominal surgery (P=0.003) and malignancy (P=0.05). Mixed candidemia was found in 10 episodes (4%); 80% grew C albicans and C glabrata. Risk factors for mixed candidemia were not significantly different from those with monomicrobial candidemia.
conclusionC albicans remains the most commonly isolated species in this setting, consistent with findings from other Canadian centres. However, non-albicans Candida species were overall predominant. Mixed-species candidemia does not appear to be more prevalent in patients with identified risk factors.
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