ReviewThe Journal of manual & manipulative therapy2013
A regional interdependence model of musculoskeletal dysfunction: research, mechanisms, and clinical implications.
Review in The Journal of manual & manipulative therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 75 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Exercise Therapy Versus Spinal Manual Therapy in Patients With Patellofemoral Pain Syndrome: Medium Term Follow-up Results of a Randomised Controlled Trial
Effect of Regional Interdepence Physical Therapy Approach on Non-structural Medial Elbow Pain
The Effect of Spinal Manipulation on Hip Extension Strength and Jump Height, A Double Blind Randomized Control Trial
Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis
Who cites it
75 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Neuromuscular characteristics of individuals with chronic ankle instability during unilateral landing tasks: a meta-analysis of electromyographic studies.Journal of orthopaedic surgery and research · 2026Pooled it
- Alternative Exercise Regimens for Stress Urinary Incontinence in Women: A Systematic Review and Meta-analysis.International urogynecology journal · 2026Pooled it
- Does chronic ankle instability patients lead to changes in biomechanical parameters associated with anterior cruciate ligament injury during landing? A systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- Effectiveness of cervicothoracic and thoracic manual physical therapy in managing upper quarter disorders - a systematic review.The Journal of manual & manipulative therapy · 2022Pooled it
- Clinical reasoning framework for thoracic spine exercise prescription in sport: a systematic review and narrative synthesis.BMJ open sport & exercise medicine · 2020Pooled it
- Thoracic spine thrust manipulation for individuals with cervicogenic headache: a crossover randomized clinical trial.The Journal of manual & manipulative therapy · 2022Trial
- Effectiveness of local exercise therapy versus spinal manual therapy in patients with patellofemoral pain syndrome: medium term follow-up results of a randomized controlled trial.BMC musculoskeletal disorders · 2021Trial
- The effect of manual therapy to the thoracic spine on pain-free grip and sympathetic activity in patients with lateral epicondylalgia humeri. A randomized, sample sized planned, placebo-controlled, patient-blinded monocentric trial.BMC musculoskeletal disorders · 2020Trial
- Operative vs non-operative management of ventral hernia: a population based study of long-term benefits and consequences.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Managing Musculoskeletal Pain Through Targeted Therapeutic Massage During Pregnancy: A Case Report.International journal of therapeutic massage & bodywork · 2026Article
- The 2023 patient profile and clinical management characteristics at a South African chiropractic training clinic: a descriptive cross-sectional study.Chiropractic & manual therapies · 2026Article
- Factors Influencing Excessive Dynamic Genu Valgum and the Effect on Post-Landing Movement Patterns: A Cross-Discipline Narrative Review.Journal of functional morphology and kinesiology · 2026Review
- Effectiveness of Thoracic Spine Manipulation for the Management of Neck Pain: A Systematic Umbrella Review with Risk of Bias and Methodological and Reporting Quality.Healthcare (Basel, Switzerland) · 2026Review
- Treatment Guidelines and Decision Tree for Dry Needling Musculoskeletal Conditions: A Consensus Statement.International journal of sports physical therapy · 2026Article
- Manual therapy considerations for adhesive capsulitis in the breast cancer population: a clinical perspective.The Journal of manual & manipulative therapy · 2025Article
- The prevalence of subclassification-based diagnoses when considering cervical contribution in shoulder pain patients: a secondary analysis from a previous research.The Journal of manual & manipulative therapy · 2025Article
- Patient-Practitioner-Environment Synchronization: Four-Step Process for Integrating Interprofessional and Distinctive Competencies in Osteopathic Practice-A Scoping Review with Integrative Hypothesis.Healthcare (Basel, Switzerland) · 2025Review
- Cervical Spine Screening Based on Movement Strategies Improves Shoulder Physical Variables in Neck-Related Shoulder Pain Patients: A Secondary Analysis from an Observational Study.Journal of clinical medicine · 2025Article
- Diagnosing and treating upper back pain: insights from New Zealand's manipulative physiotherapists and osteopaths.The Journal of manual & manipulative therapy · 2025Article
- Regional interdependence between senile kyphosis and cervical postural syndrome: a case report.AME case reports · 2025Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term 'regional interdependence' or RI has recently been introduced into the vernacular of physical therapy and rehabilitation literature as a clinical model of musculoskeletal assessment and intervention. The underlying premise of this model is that seemingly unrelated impairments in remote anatomical regions of the body may contribute to and be associated with a patient's primary report of symptoms. The clinical implication of this premise is that interventions directed at one region of the body will often have effects at remote and seeming unrelated areas. The formalized concept of RI is relatively new and was originally derived in an inductive manner from a variety of earlier publications and clinical observations. However, recent literature has provided additional support to the concept. The primary purpose of this article will be to further refine the operational definition for the concept of RI, examine supporting literature, discuss possible clinically relevant mechanisms, and conclude with a discussion of the implications of these findings on clinical practice and research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.