Evidence map›Paper›PMID 24419863›Full record

ReviewCurrent osteoporosis reports2014

Bone metabolism in anorexia nervosa.

Pouneh K Fazeli, Anne Klibanski

Open access · greenAbstract readReview
In one paragraph

Review in Current osteoporosis reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Effects of teriparatide on hip structure and bone microarchitecture in women with anorexia nervosa: a placebo-controlled randomized trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Trial
  3. Article
  4. Article
  5. Article
  6. In premenopausal women with idiopathic osteoporosis, lower bone formation rate is associated with higher body fat and higher IGF-1.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  7. Review
  8. Review
  9. Review
  10. Eating disorders and bone metabolism in women.Current opinion in pediatrics · 2017
    Review
  11. Bone-Fat Interaction.Endocrinology and metabolism clinics of North America · 2017
    Review
  12. Article
  13. An overview of the metabolic functions of osteocalcin.Current osteoporosis reports · 2015
    Review
  14. An overview of the metabolic functions of osteocalcin.Reviews in endocrine & metabolic disorders · 2015
    Review
  15. Anorexia nervosa - medical complications.Journal of eating disorders · 2015
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pouneh K FazeliNeuroendocrine Unit, Massachusetts General Hospital, 55 Fruit Street, Bulfinch 457, Boston, MA, 02114, USA, pkfazeli@partners.org.
Anne Klibanski
Massachusetts General Hospital · US

Funding

Interdisciplinary Study of Marrow Adiposity, Mineral Metabolism & Energy BalanceR24DK092759 · NIDDK · MAINEHEALTH · PI HOROWITZ, MARK C, MACDOUGALD, ORMOND A · 2011 to 2019
$13.0M
The Role of PTH in the Low Bone Mass of Anorexia NervosaK23DK094820 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI FAZELI, POUNEH KHADEJEH · 2012 to 2015
$746k
NIDDK NIH HHS K23 DK094820NIDDK NIH HHS R24 DK092759
6 · The paper itself

Abstract

Anorexia nervosa (AN), a psychiatric disorder predominantly affecting young women, is characterized by self-imposed, chronic nutritional deprivation and distorted body image. AN is associated with a number of medical comorbidities including low bone mass. The low bone mass in AN is due to an uncoupling of bone formation and bone resorption, which is the result of hormonal adaptations aimed at decreasing energy expenditure during periods of low energy intake. Importantly, the low bone mass in AN is associated with a significant risk of fractures and therefore treatments to prevent bone loss are critical. In this review, we discuss the hormonal determinants of low bone mass in AN and treatments that have been investigated in this population.

Indexed as

Anorexia NervosaBone DensityBone Diseases, MetabolicBone ResorptionHuman Growth HormoneHumansHypogonadismHypothalamo-Hypophyseal SystemOsteogenesisPituitary-Adrenal SystemHuman Growth Hormone

Identifiers

PMID24419863
PMCPMC3936314
OpenAlexW1982927793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.