Evidence map›Paper›PMID 24419521›Full record

ReviewBone marrow transplantation2014

Clinical guide to fertility preservation in hematopoietic cell transplant recipients.

S Joshi, B N Savani, E J Chow, M H Gilleece, J Halter, D A Jacobsohn, J Pidala, G P Quinn, J-Y Cahn, A A Jakubowski and 11 more

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bone marrow transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 19 institutions in 5 countries.

S JoshiNationwide Children's Hospital, Columbus, OH, USA.
B N SavaniVanderbilt University Medical Center, Nashville, TN, USA.
E J ChowFred Hutchinson Cancer Research Center, Seattle, WA, USA.
M H GilleeceDepartment of Haematology, St. James's University Hospital, Leeds, UK.
J HalterDivision of Hematology, University Hospital Basel, Basel, Switzerland.
D A JacobsohnDivision of Blood and Marrow Transplantation, Children's National Medical Center, Washington, DC, USA.
J PidalaBlood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL, USA.
G P QuinnDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
J-Y CahnDepartment of Hematology, University Hospital, Grenoble, France.
A A JakubowskiDivision of Hematologic Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
N R KamaniCenter for Cancer and Blood Disorders, Children's National Medical Center, Washington, DC, USA.
H M LazarusSeidman Cancer Center, University Hospitals Case Medical Center, Cleveland, OH, USA.
J D RizzoCenter for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI, USA.
H C SchoutenUniversity Hospital Maastricht, Maastricht, The Netherlands.
G SocieHopital Saint Louis, Paris, France.
P StrattonEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
M L SorrorFred Hutchinson Cancer Research Center, Seattle, WA, USA.
A B WarwickDepartment of Pediatrics, Uniformed Services University, Bethesda, MD, USA.
J R WingardBone Marrow Transplant, Shands HealthCare, University of Florida, Gainesville, FL, USA.
A W LorenPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
N S MajhailCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program, Minneapolis, MN, USA.
Fred Hutch Cancer Center · USMoffitt Cancer Center · USCenter for Cancer and Blood Disorders · USChildren's National · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USHôpital Saint-Louis · FRMaastricht University Medical Centre · NLMedical College of Wisconsin · USMemorial Sloan Kettering Cancer Center · USNational Marrow Donor Program · USNationwide Children's Hospital · USSt James's University Hospital · GBUF Health Shands Hospital · USUniformed Services University of the Health Sciences · USUniversité Grenoble Alpes · FRUniversity Hospital of Basel · CHUniversity Hospitals Case Medical Center · USUniversity of Pennsylvania · USVanderbilt University Medical Center · US

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
PB vs. BMU01HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2001 to 2010
$63.3M
Safety and Immunogenicity of Gardasil post stem cell transplantationZIAHD008900 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI STRATTON, PAMELA · 2010 to 2016
$1.2M
NCI NIH HHS U24 CA076518NCI NIH HHS U24-CA76518NHLBI NIH HHS 5U01HL069294NHLBI NIH HHS U01 HL069294PHS HHS HHSH234200637015C
6 · The paper itself

Abstract

With broadening indications, more options for hematopoietic cell transplantation (HCT) and improvement in survival, the number of long-term HCT survivors is expected to increase steadily. Infertility is a frequent problem that long-term HCT survivors and their partners face and it can negatively impact on the quality of life. The most optimal time to address fertility issues is before the onset of therapy for the underlying disease; however, fertility preservation should also be addressed before HCT in all children and patients of reproductive age, with referral to a reproductive specialist for patients interested in fertility preservation. In vitro fertilization (IVF) and embryo cryopreservation, oocyte cryopreservation and ovarian tissue banking are acceptable methods for fertility preservation in adult women/pubertal females. Sperm banking is the preferred method for adult men/pubertal males. Frequent barriers to fertility preservation in HCT recipients may include the perception of lack of time to preserve fertility given an urgency to move ahead with transplant, lack of patient-physician discussion because of several factors (for example, time constraints, lack of knowledge), inadequate access to reproductive specialists, and costs and lack of insurance coverage for fertility preservation. There is a need to raise awareness in the medical community about fertility preservation in HCT recipients.

Indexed as

FemaleFertility PreservationHematopoietic Stem Cell TransplantationHumansMalePregnancyTransplantation ConditioningTransplantation, Homologous

Identifiers

PMID24419521
PMCPMC4071767
OpenAlexW1974765254

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.