ArticleScientific reports2014
Comprehensive analysis of GnRH2 neuronal projections in zebrafish.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Single-nuclei RNA sequencing reveals heterogeneity within developing GnRH3 neurons in zebrafish.Journal of neuroendocrinology · 2026Article
- Effects of environmental salinity on global and endocrine-specific transcriptomic profiles in the caudal neurosecretory system of salmonid fishes.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Differential involvement of cAMP/PKA-, PLC/PKC- and CaFrontiers in endocrinology · 2024Article
- Novel pituitary actions of GnRH in teleost: The link between reproduction and feeding regulation.Frontiers in endocrinology · 2022Article
- Gnrh2 maintains reproduction in fasting zebrafish through dynamic neuronal projection changes and regulation of gonadotropin synthesis, oogenesis, and reproductive behaviors.Scientific reports · 2021Article
- Role of Habenula in Social and Reproductive Behaviors in Fish: Comparison With Mammals.Frontiers in behavioral neuroscience · 2021Review
- Expression profile of kisspeptin2 and gonadotropin-releasing hormone2 mRNA during photo-thermal and melatonin treatments in the female air-breathing catfish Heteropneustes fossilis.Fish physiology and biochemistry · 2020Article
- Seasonal Related Multifactorial Control of Pituitary Gonadotropin and Growth Hormone in Female Goldfish: Influences of Neuropeptides and Thyroid Hormone.Frontiers in endocrinology · 2020Article
- Neuroendocrinology of reproduction: Is gonadotropin-releasing hormone (GnRH) dispensable?Frontiers in neuroendocrinology · 2019Review
- Localization of three forms of gonadotropin-releasing hormone in the brain and pituitary of the self-fertilizing fish, Kryptolebias marmoratus.Fish physiology and biochemistry · 2019Article
- Multiple functions of non-hypophysiotropic gonadotropin releasing hormone neurons in vertebrates.Zoological letters · 2019Review
- A Type IIb, but Not Type IIa, GnRH Receptor Mediates GnRH-Induced Release of Growth Hormone in the Ricefield Eel.Frontiers in endocrinology · 2018Article
- GnRH-mediated olfactory and visual inputs promote mating-like behaviors in male zebrafish.PloS one · 2017Article
- Conservation of Three-Dimensional Helix-Loop-Helix Structure through the Vertebrate Lineage Reopens the Cold Case of Gonadotropin-Releasing Hormone-Associated Peptide.Frontiers in endocrinology · 2017Article
- Targeted Mutagenesis of the Hypophysiotropic Gnrh3 in Zebrafish (Danio rerio) Reveals No Effects on Reproductive Performance.PloS one · 2016Article
- Photoperiodic Modulation of Circadian Clock and Reproductive Axis Gene Expression in the Pre-Pubertal European Sea Bass Brain.PloS one · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence and conservation of GnRH2 across vertebrate species suggest important biological roles. However, the function of GnRH2 remains unclear. A good research model for GnRH2 functional studies is still lacking largely due to the absence of GnRH2 in the widely used mouse model. Hence, we used the zebrafish, for which powerful genetic tools are available, and developed a transgenic (Tg) line expressing enhanced green fluorescence protein (eGFP). The high sensitivity of eGFP, which can diffuse throughout the neuron, enables us to document the complete projectome of GnRH2 neurons at different developmental stages. Fine projection structures were observed without sacrificing the fish. Crossed with the GnRH3:tdTomato Tg line, the GnRH2:eGFP Tg line provides us with an opportunity to visualize the entire GnRH system simultaneously in one organism. This work will provide a framework to understand the function of the highly-conserved GnRH2 system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.