ArticleJournal of acquired immune deficiency syndromes (1999)2014
Age, race/ethnicity, and behavioral risk factors associated with per contact risk of HIV infection among men who have sex with men in the United States.
Article in Journal of acquired immune deficiency syndromes (1999), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Association of nitrite inhalants use and unprotected anal intercourse and HIV/syphilis infection among MSM in China: a systematic review and meta-analysis.BMC public health · 2020Pooled it
- Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2018Pooled it
- Estimating per-act HIV transmission risk: a systematic review.AIDS (London, England) · 2014Pooled it
- Predictors of Long-Term HIV Pre-exposure Prophylaxis Adherence After Study Participation in Men Who Have Sex With Men.Journal of acquired immune deficiency syndromes (1999) · 2019Trial
- Feasibility, Acceptability, and Tolerability of Targeted Naltrexone for Nondependent Methamphetamine-Using and Binge-Drinking Men Who Have Sex with Men.Journal of acquired immune deficiency syndromes (1999) · 2016Trial
- Integrated analysis of rectal mucosal microbiome and transcriptome reveals a distinct microenvironment among young MSM.JCI insight · 2024Article
- The rectal mucosal immune environment and HIV susceptibility among young men who have sex with men.Frontiers in immunology · 2022Article
- Motivations for opioid and stimulant use among drug using black sexual minority men: A life course perspective.Drug and alcohol dependence · 2020Article
- Lack of sexual behavior disclosure may distort STI testing outcomes.BMC public health · 2020Article
- Genetic Network Analysis to Assess the Risk of Human Immunodeficiency Virus Transmission Among Men Who Have Sex With Men Seeking Partners on the Internet.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Modeling methods for estimating HIV incidence: a mathematical review.Theoretical biology & medical modelling · 2020Review
- Development and Validation of the Personalized Sexual Health Promotion (SexPro) HIV Risk Prediction Model for Men Who Have Sex with Men in the United States.AIDS and behavior · 2020Article
- Alterations to the Gastrointestinal Microbiome Associated with Methamphetamine Use among Young Men who have Sex with Men.Scientific reports · 2019Article
- Four Decades of Epidemiologic Science on HIV Infection and Disease, and Its Impact on Public Health Practice and Policy for Sexual and Gender Minority Persons.Delaware journal of public health · 2019Article
- Strategies used by gay male HIV serodiscordant couples to reduce the risk of HIV transmission from anal intercourse in three countries.Journal of the International AIDS Society · 2019Article
- Latent Classes of Sexual Risk Among Black Men Who Have Sex with Men and Women.Archives of sexual behavior · 2018Article
- Age Cohort Differences in Sexual Behaviors Among Black Men Who Have Sex With Men and Women.Journal of sex research · 2018Article
- Methamphetamine augment HIV-1 Tat mediated memory deficits by altering the expression of synaptic proteins and neurotrophic factors.Brain, behavior, and immunity · 2018Article
- Use of poppers and HIV risk behaviours among men who have sex with men in Paris, France: an observational study.Sexual health · 2018Observational
- Expert consensus statement on the science of HIV in the context of criminal law.Journal of the International AIDS Society · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveYoung men who have sex with men (MSM) and MSM of color have the highest HIV incidence in the United States. To explore possible explanations for these disparities and known individual risk factors, we analyzed the per contact risk (PCR) of HIV seroconversion in the early highly active antiretroviral therapy era.
methodsData from 3 longitudinal studies of MSM (HIV Network for Prevention Trials Vaccine Preparedness Study, EXPLORE behavioral efficacy trial, and VAX004 vaccine efficacy trial) were pooled. The analysis included visits where participants reported unprotected receptive anal intercourse (URA), protected receptive anal intercourse, or unprotected insertive anal intercourse (UIA) with an HIV seropositive, unknown HIV serostatus, or an HIV seronegative partner. We used regression standardization to estimate average PCRs for each type of contact, with bootstrap confidence intervals.
resultsThe estimated PCR was highest for URA with an HIV seropositive partner (0.73%; 95% bootstrap confidence interval [BCI]: 0.45% to 0.98%) followed by URA with a partner of unknown HIV serostatus (0.49%; 95% BCI: 0.32% to 0.62%). The estimated PCR for protected receptive anal intercourse and UIA with an HIV seropositive partner was 0.08% (95% BCI: 0.0% to 0.19%) and 0.22% (95% BCI: 0.05% to 0.39%), respectively. Average PCRs for URA and UIA with HIV seropositive partners were higher by 0.14%-0.34% among younger participants and higher by 0.08% for UIA among Latino participants compared with white participants. Estimated PCRs increased with the increasing number of sexual partners, use of methamphetamines or poppers, and history of sexually transmitted infection.
conclusionsSusceptibility or partner factors may explain the higher HIV conversion risk for younger MSM, some MSM of color, and those reporting individual risk factors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.