Evidence map›Paper›PMID 24418806›Full record

ReviewNature reviews. Urology2014

Reducing infection rates after prostate biopsy.

Florian M E Wagenlehner, Adrian Pilatz, Przemyslaw Waliszewski, Wolfgang Weidner, Truls E Bjerklund Johansen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Rectal E. coli above ciprofloxacin ECOFF associate with infectious complications following prostate biopsy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
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  7. Transrectal prostate biopsy: easy, effective and safe.Prostate cancer and prostatic diseases · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Florian M E WagenlehnerClinic for Urology, Paediatric Urology and Andrology, Justus-Liebig-University, Rudolf-Buchheim Strasse 7, 35392 Giessen, Germany.
Adrian PilatzClinic for Urology, Paediatric Urology and Andrology, Justus-Liebig-University, Rudolf-Buchheim Strasse 7, 35392 Giessen, Germany.
Przemyslaw WaliszewskiClinic for Urology, Paediatric Urology and Andrology, Justus-Liebig-University, Rudolf-Buchheim Strasse 7, 35392 Giessen, Germany.
Wolfgang WeidnerClinic for Urology, Paediatric Urology and Andrology, Justus-Liebig-University, Rudolf-Buchheim Strasse 7, 35392 Giessen, Germany.
Truls E Bjerklund JohansenUrologic Clinic, Oslo University Hospital, P. O. Box 4959 Nydalen, N-0424 Oslo, Norway.
University of Giessen · DEOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the years, prostate biopsy has become the gold-standard technique for diagnosing prostate carcinoma. Worldwide, several million prostate biopsies are performed every year, most commonly using the transrectal approach. Preoperative antibiotic prophylaxis with fluoroquinolones has been shown to be effective for reducing infection rates. However, in recent years, an increase in febrile infection rates after transrectal prostate biopsy (from 1% to 4%) has been reported in retrospective and prospective studies. The predominant risk factor for infection seems to be the presence of fluoroquinolone-resistant bacteria in faeces. Patients at risk of fluoroquinolone resistance should receive carefully selected antibiotics at sufficient concentrations to be effective. Targeted prophylaxis after rectal flora swabbing has been shown to be efficacious compared with empirical antibiotic prophylaxis. Several forms of bowel preparations are under investigation, although none have yet been shown to significantly reduce infection rates. Perineal prostate biopsy is currently being evaluated as a strategy for preventing the inoculation of rectal flora, but limited data support this approach at present.

Indexed as

AlgorithmsAntibiotic ProphylaxisBacterial InfectionsBiopsy, NeedleHumansIncidenceMale

Identifiers

PMID24418806
OpenAlexW2094031763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.