Evidence map›Paper›PMID 24418679›Full record

ArticleOsteoarthritis and cartilage2014

Body mass index is not a clinically meaningful predictor of patient reported outcomes of primary hip replacement surgery: prospective cohort study.

A Judge, R N Batra, G E Thomas, D Beard, M K Javaid, D W Murray, P A Dieppe, K E Dreinhoefer, K Peter-Guenther, R Field and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Osteoarthritis and cartilage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Observational
  19. Article
  20. Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status.The Journal of bone and joint surgery. American volume · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

A JudgeOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK. Electronic address: andrew.judge@ndorms.ox.ac.uk.
R N BatraOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK. Electronic address: rajbir.batra@ndorms.ox.ac.uk.
G E ThomasOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK. Electronic address: geraint.thomas@ndorms.ox.ac.uk.
D BeardOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK. Electronic address: david.beard@ndorms.ox.ac.uk.
M K JavaidOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK. Electronic address: kassim.javaid@ndorms.ox.ac.uk.
D W MurrayOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK. Electronic address: david.murray@ndorms.ox.ac.uk.
P A DieppePeninsula College of Medicine and Dentistry, C420, Portland Square, University of Plymouth Campus, Drake Circus, Plymouth PL4 8AA, UK. Electronic address: p.dieppe@exeter.ac.uk.
K E DreinhoeferInstitute for Muskuloskeletal Rehabilitation, Prevention and Health Service Research, Center for Sport Science and Sport Medicine (CSSB), Center for Musculoskeletal Surgery (CMSC), Charité Universitätsmedizin Berlin, Philippstraße 13, 10115 Berlin, Germany; Department of Orthopaedics, Traumatology and Sports Medicine, Medical Park Berlin Humboldtmühle, An der Mühle 2-9, D-13507 Berlin, Germany. Electronic address: karsten.dreinhoefer@charite.de.
K Peter-GuentherDepartment of Orthopaedic Surgery, University Hospital Carl Gustav Carus, Medical Faculty of the Technical University of Dresden, Germany. Electronic address: klaus-peter.guenther@uniklinikum-dresden.de.
R FieldElective Orthopaedic Centre, Dorking Road, Epsom, Surrey KT18 7EG, UK. Electronic address: richard.field@eoc.nhs.uk.
C CooperOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK. Electronic address: cc@mrc.soton.ac.uk.
N K ArdenOxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK. Electronic address: nigel.arden@ndorms.ox.ac.uk.

Funding

Department of Health RP-PG-0407-10064Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_UP_A620_1014Medical Research Council MC_UU_12011/1
6 · The paper itself

Abstract

objectivesTo describe whether body mass index (BMI) is a clinically meaningful predictor of patient reported outcomes following primary total hip replacement (THR) surgery.

designCombined data from prospective cohort studies. We obtained information from four cohorts of patients receiving primary THR for osteoarthritis: Exeter Primary Outcomes Study (EPOS) (n = 1431); EUROHIP (n = 1327); Elective Orthopaedic Centre (n = 2832); and St. Helier (n = 787). The exposure of interest was pre-operative BMI. Confounding variables included: age, sex, SF-36 mental health, comorbidities, fixed flexion, analgesic use, college education, OA in other joints, expectation of less pain, radiographic K&L grade, ASA grade, years of hip pain. The primary outcome was the Oxford Hip Score (OHS). Regression models describe the association of BMI on outcome adjusting for all confounders.

resultsFor a 5-unit increase in BMI, the attained 12-month OHS decreases by 0.78 points 95%CI (0.27-1.28), P-value 0.001. Compared to people of normal BMI (20-25), those in the obese class II (BMI 35-40) would have a 12-month OHS that is 2.34 points lower. Although statistically significant this effect is small and not clinically meaningful in contrast to the substantial change in OHS seen across all BMI groupings. In obese class II patients achieved a 22.2 point change in OHS following surgery.

conclusionsPatients achieved substantial change in OHS after THR across all BMI categories, which greatly outweighs the small difference in attained post-operative score. The findings suggest BMI should not present a barrier to access THR in terms of PROMs.

Indexed as

Body Mass IndexPatient Outcome AssessmentAgedAged, 80 and overArthroplasty, Replacement, HipFemaleHumansMaleMiddle AgedOsteoarthritis, HipPainPatient SatisfactionPostoperative PeriodProspective StudiesQuality of LifeRisk FactorsBody mass indexDecision makingEpidemiologyHip replacementOsteoarthritisPatient reported outcome

Identifiers

PMID24418679
PMCPMC4147658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.