Evidence map›Paper›PMID 24418501›Full record

ArticleNeuroImage2014

Motion compensation for brain PET imaging using wireless MR active markers in simultaneous PET-MR: phantom and non-human primate studies.

Chuan Huang, Jerome L Ackerman, Yoann Petibon, Marc D Normandin, Thomas J Brady, Georges El Fakhri, Jinsong Ouyang

Abstract read
In one paragraph

Article in NeuroImage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of List-Mode-Based Intraframe Motion Correction in Dynamic Brain PET Imaging.IEEE transactions on radiation and plasma medical sciences · 2024
    Article
  4. Review
  5. Synergistic motion compensation strategies for positron emission tomography when acquired simultaneously with magnetic resonance imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Review
  6. Quantitative PET in the 2020s: a roadmap.Physics in medicine and biology · 2021
    Article
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  8. Article
  9. Article
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  11. Review
  12. Article
  13. Strain Map of the Tongue in Normal and ALS Speech Patterns from Tagged and Diffusion MRI.Proceedings of SPIE--the International Society for Optical Engineering · 2018
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Chuan HuangCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Radiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: huang.chuan@mgh.harvard.edu.
Jerome L AckermanDepartment of Radiology, Harvard Medical School, Boston, MA 02115, USA; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA. Electronic address: jerry@nmr.mgh.harvard.edu.
Yoann PetibonCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA; Laboratoire d'imagerie fonctionnelle (LIF), UMRS-678, INSERM, Université Pierre et Marie Curie, CHU Pitié-Salpêtrière, Paris, France. Electronic address: petibon@pet.mgh.harvard.edu.
Marc D NormandinCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Radiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: normandin.marc@mgh.harvard.edu.
Thomas J BradyCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Radiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: tom@nmr.mgh.harvard.edu.
Georges El FakhriCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Radiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: elfakhri@pet.mgh.harvard.edu.
Jinsong OuyangCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Radiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: ouyang.jinsong@mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · USGordon Center for Medical Imaging · USSorbonne Université · FR

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Quantitative Oncologic PET-MRR01CA165221 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2012 to 2023
$4.7M
Combined PET and fMRI imaging of dopamine and serotonin responses in depressionR01MH100350 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI NORMANDIN, MARC DAVID · 2013 to 2017
$2.6M
Quantitative Cardiac PETR01HL110241 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2011 to 2014
$1.9M
Motion Compensation in Simultaneous PET-MRR21EB012326 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2010 to 2011
$470k
NCI NIH HHS R01 CA165221NCI NIH HHS R01-CA165221NHLBI NIH HHS R01 HL110241NIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41-EB015896NIBIB NIH HHS R21 EB012326NIBIB NIH HHS R21-EB012326NIMH NIH HHS R01 MH100350NIMH NIH HHS R01-MH100350
6 · The paper itself

Abstract

Brain PET scanning plays an important role in the diagnosis, prognostication and monitoring of many brain diseases. Motion artifacts from head motion are one of the major hurdles in brain PET. In this work, we propose to use wireless MR active markers to track head motion in real time during a simultaneous PET-MR brain scan and incorporate the motion measured by the markers in the listmode PET reconstruction. Several wireless MR active markers and a dedicated fast MR tracking pulse sequence module were built. Data were acquired on an ACR Flangeless PET phantom with multiple spheres and a non-human primate with and without motion. Motions of the phantom and monkey's head were measured with the wireless markers using a dedicated MR tracking sequence module. The motion PET data were reconstructed using list-mode reconstruction with and without motion correction. Static reference was used as gold standard for quantitative analysis. The motion artifacts, which were prominent on the images without motion correction, were eliminated by the wireless marker based motion correction in both the phantom and monkey experiments. Quantitative analysis was performed on the phantom motion data from 24 independent noise realizations. The reduction of bias of sphere-to-background PET contrast by active marker based motion correction ranges from 26% to 64% and 17% to 25% for hot (i.e., radioactive) and cold (i.e., non-radioactive) spheres, respectively. The motion correction improved the channelized Hotelling observer signal-to-noise ratio of the spheres by 1.2 to 6.9 depending on their locations and sizes. The proposed wireless MR active marker based motion correction technique removes the motion artifacts in the reconstructed PET images and yields accurate quantitative values.

Indexed as

Head MovementsWireless TechnologyAlgorithmsAnimalsArtifactsElectrocardiographyHumansImage Processing, Computer-AssistedMacaca mulattaMagnetic Resonance ImagingPhantoms, ImagingPositron-Emission TomographyRadiopharmaceuticalsSignal-To-Noise RatioRadiopharmaceuticalsActive markerBrain PETMotion correctionSimultaneous PET–MR

Identifiers

PMID24418501
PMCPMC3965607
OpenAlexW2070042306

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.