Observational studyJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2014
Rate of improvement of CF life expectancy exceeds that of general population--observational death registration study.
Observational study in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis.The Cochrane database of systematic reviews · 2019Pooled it
- Pain and its clinical associations in individuals with cystic fibrosis: A systematic review.Chronic respiratory disease · 2016Pooled it
- Impact of CFTR Modulators on Longitudinal Cystic Fibrosis Survival and Mortality: Review and Secondary Analysis.Pulmonary therapy · 2025Review
- Paranasal Sinus Hypoplasia and Sinonasal Anatomical Variants in Cystic Fibrosis Adult Patients: A Computed- Tomography-Based Volumetric Comparison with Healthy Controls.Journal of clinical medicine · 2025Article
- Oral health and related outcomes in children and adolescents with cystic fibrosis: a scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Case Report: When cystic fibrosis, elexacaftor/tezacaftor/ivacaftor therapy, and alpha1 antitrypsin deficiency get together.Frontiers in pediatrics · 2024Article
- Ruthenium(II) Polypyridyl Complexes for Antimicrobial Photodynamic Therapy: Prospects for Application in Cystic Fibrosis Lung Airways.Pharmaceutics · 2022Article
- A dual center and dual vendor comparison study of automated perfusion-weighted phase-resolved functional lung magnetic resonance imaging with dynamic contrast-enhanced magnetic resonance imaging in patients with cystic fibrosis.Pulmonary circulation · 2022Article
- Review
- Capsaicin-Loaded Chitosan Nanocapsules for wtCFTR-mRNA Delivery to a Cystic Fibrosis Cell Line.Biomedicines · 2020Article
- Activated L-Arginine/Nitric Oxide Pathway in Pediatric Cystic Fibrosis and Its Association with Pancreatic Insufficiency, Liver Involvement and Nourishment: An Overview and New Results.Journal of clinical medicine · 2020Article
- Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.The Journal of clinical investigation · 2020Article
- Quantifying Sex Bias in Clinical Studies at Scale With Automated Data Extraction.JAMA network open · 2019Article
- Opportunistic bacteria confer the ability to ferment prebiotic starch in the adult cystic fibrosis gut.Gut microbes · 2019Article
- Cystic Fibrosis: Clinical Phenotypes in Children and Adolescents.Pediatric gastroenterology, hepatology & nutrition · 2018Article
- Evaluation of Food Insecurity in Adults and Children With Cystic Fibrosis: Community Case Study.Frontiers in public health · 2018Article
- Early Respiratory Bacterial Detection and Antistaphylococcal Antibiotic Prophylaxis in Young Children with Cystic Fibrosis.Annals of the American Thoracic Society · 2018Observational
- Exercise performance and quality of life in children with cystic fibrosis and mildly impaired lung function: relation with antibiotic treatments and hospitalization.European journal of pediatrics · 2017Article
- Lung function imaging methods in Cystic Fibrosis pulmonary disease.Respiratory research · 2017Review
- Cystic fibrosis: a clinical view.Cellular and molecular life sciences : CMLS · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundIt is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement.
methodDeath registration data analysis (US, England & Wales (E&W)-1972-2009).
resultsCF median age of death is higher in US than E&W and greater for males, opposite to that of death from all causes. CF median age of death has increased by 0.543 life years per year (E&W, US combined (95% confidence interval 0.506, 0.582)). The difference in median age at death between those dying from all causes and CF decreased in both territories. CF median age of death for males is greater than for females in both territories. This gap has not narrowed.
conclusionThe median age of death of people with CF is improving more rapidly than that of the general population in US and E&W.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.