Evidence map›Paper›PMID 24417885›Full record

ReviewCritical care (London, England)2014

How to assess prognosis after cardiac arrest and therapeutic hypothermia.

Fabio Taccone, Tobias Cronberg, Hans Friberg, David Greer, Janneke Horn, Mauro Oddo, Sabino Scolletta, Jean-Louis Vincent

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Critical care (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03195881 (Post Cardiac Arrest Neuroprognostication Using the Diameter of Optic Nerve Sheath Via Ocular ultRAsound), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
18.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03195881 completednot on this mapstarted 2017, after this paper: background citation

Post Cardiac Arrest Neuroprognostication Using the Diameter of Optic Nerve Sheath Via Ocular ultRAsound

TypeobservationalSponsorTriHealth Inc.Ran2017 to 2019Enrolled25ConditionsHeart Arrest, Intracranial Pressure IncreaseArmsOcular ultrasound
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 123 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 6 countries.

Fabio Taccone
Tobias Cronberg
Hans Friberg
David Greer
Janneke Horn
Mauro Oddo
Sabino Scolletta
Jean-Louis Vincent
Lund University · SEAcademic Medical Center · NLErasmus Hospital · BETemple University · USUniversité Libre de Bruxelles · BEUniversity Hospital of Lausanne · CHUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of patients who are admitted in a comatose state following successful resuscitation after cardiac arrest remains uncertain. Although the introduction of therapeutic hypothermia (TH) and improvements in post-resuscitation care have significantly increased the number of patients who are discharged home with minimal brain damage, short-term assessment of neurological outcome remains a challenge. The need for early and accurate prognostic predictors is crucial, especially since sedation and TH may alter the neurological examination and delay the recovery of motor response for several days. The development of additional tools, including electrophysiological examinations (electroencephalography and somatosensory evoked potentials), neuroimaging and chemical biomarkers, may help to evaluate the extent of brain injury in these patients. Given the extensive literature existing on this topic and the confounding effects of TH on the strength of these tools in outcome prognostication after cardiac arrest, the aim of this narrative review is to provide a practical approach to post-anoxic brain injury when TH is used. We also discuss when and how these tools could be combined with the neurological examination in a multimodal approach to improve outcome prediction in this population.

Indexed as

BiomarkersBrain InjuriesComaElectroencephalographyEvoked Potentials, SomatosensoryFemaleHeart ArrestHumansHypothermia, InducedMaleMiddle AgedNeurologic ExaminationPrognosisBiomarkers

Identifiers

PMID24417885
PMCPMC4056000
OpenAlexW2110031777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.