Evidence map›Paper›PMID 24416316›Full record

Trial reportPloS one2014

Effect of integrated capacity-building interventions on malaria case management by health professionals in Uganda: a mixed design study with pre/post and cluster randomized trial components.

Martin Kayitale Mbonye, Sarah M Burnett, Aldomoro Burua, Robert Colebunders, Ian Crozier, Stephen N Kinoti, Allan Ronald, Sarah Naikoba, Timothy Rubashembusya, Jean-Pierre Van Geertruyden and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Martin Kayitale MbonyeTraining Department, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Sarah M BurnettAccordia Global Health Foundation, Washington DC, United States of America.
Aldomoro BuruaManagement Sciences for Health, Kampala, Uganda.
Robert ColebundersDepartment of Epidemiology and Social Medicine, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium ; Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Ian CrozierAccordia Global Health Foundation, Washington DC, United States of America.
Stephen N KinotiCenter for Human Services, University Research Co., LLC, Bethesda, Maryland, United States of America ; Fio Corporation, Toronto, Ontario, Canada.
Allan RonaldDepartment of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Sarah NaikobaTraining Department, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Timothy RubashembusyaTraining Department, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Jean-Pierre Van GeertruydenDepartment of Epidemiology and Social Medicine, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Kelly S WillisAccordia Global Health Foundation, Washington DC, United States of America.
Marcia R WeaverDepartments of Global Health and Health Services, University of Washington, Seattle, Washington, United States of America.
Accordia Global Health Foundation · USInfectious Diseases Institute · UGUniversity of Antwerp · BEMakerere University · UGUniversity of Manitoba · CAUniversity of Washington · USUniversity Research Co (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Integrated Infectious Diseases Capacity Building Evaluation (IDCAP) designed two interventions: Integrated Management of Infectious Disease (IMID) training program and On-Site Support (OSS). We evaluated their effects on 23 facility performance indicators, including malaria case management. METHODOLOGY: IMID, a three-week training with two follow-up booster courses, was for two mid- level practitioners, primarily clinical officers and registered nurses, from 36 primary care facilities. OSS was two days of training and continuous quality improvement activities for nine months at 18 facilities, to which all health workers were invited to participate. Facilities were randomized as clusters 1∶1 to parallel OSS "arm A" or control "arm B". Outpatient data on four malaria case management indicators were collected for 14 months. Analysis compared changes before and during the interventions within arms (relative risk = RR). The effect of OSS was measured with the difference in changes across arms (ratio of RR = RRR).

findingsThe proportion of patients with suspected malaria for whom a diagnostic test result for malaria was recorded decreased in arm B (adjusted RR (aRR) = 0.97; 99%CI: 0.82,1.14) during IMID, but increased 25% in arm A (aRR = 1.25; 99%CI:0.94, 1.65) during IMID and OSS relative to baseline; (aRRR = 1.28; 99%CI:0.93, 1.78). The estimated proportion of patients that received an appropriate antimalarial among those prescribed any antimalarial increased in arm B (aRR = 1.09; 99%CI: 0.87, 1.36) and arm A (aRR = 1.50; 99%CI: 1.04, 2.17); (aRRR = 1.38; 99%CI: 0.89, 2.13). The proportion of patients with a negative diagnostic test result for malaria prescribed an antimalarial decreased in arm B (aRR = 0.96; 99%CI: 0.84, 1.10) and arm A (aRR = 0.67; 99%CI: 0.46, 0.97); (aRRR = 0.70; 99%CI: 0.48, 1.00). The proportion of patients with a positive diagnostic test result for malaria prescribed an antibiotic did not change significantly in either arm.

interpretationThe combination of IMID and OSS was associated with statistically significant improvements in malaria case management.

Indexed as

AntimalarialsCapacity BuildingCase ManagementChildChild, PreschoolFemaleHealth PersonnelHumansMalariaMaleQuality of Health CareUgandaAntimalarials

Identifiers

PMID24416316
PMCPMC3885656
OpenAlexW2048878358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.