ArticlePloS one2014
The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 65 citations in OpenAlex.
- Evolutionary Analysis and Expression Profiling of the TIFY Gene Family in Banana Under Multiple Stresses and Functional Characterization ofInternational journal of molecular sciences · 2026Article
- The transcriptional dynamics of TIFY/JAZ and BBX families in jasmonate signaling reveal SlBBX17 as a positive regulator of tomato defense.Plant cell reports · 2026Article
- Genome-Wide Analysis of theBiology · 2026Article
- The PEAPOD repressor complex in Arabidopsis stomatal development.Frontiers in plant science · 2025Review
- Genome-wide survey and expression analysis of JAZ genes in watermelon (Citrullus lanatus).Molecular biology reports · 2024Article
- Molecular tagging of seed size using MITE markers in an induced large seed mutant with higher cotyledon cell size in groundnut.3 Biotech · 2024Article
- Understanding the Molecular Regulatory Networks of Seed Size in Soybean.International journal of molecular sciences · 2024Review
- Site-directed mutagenesis of soybeanPlant biotechnology (Tokyo, Japan) · 2023Article
- The Non-JAZ TIFY Protein TIFY8 ofInternational journal of molecular sciences · 2023Article
- scCloudMine: A cloud-based app for visualization, comparison, and exploration of single-cell transcriptomic data.Plant communications · 2022Article
- Interactome of Arabidopsis Thaliana.Plants (Basel, Switzerland) · 2022Article
- Article
- Identification of stably expressed reference genes for expression studies inFrontiers in plant science · 2022Article
- Transcriptome-Wide Identification and Characterization of theInternational journal of molecular sciences · 2021Article
- Novel nucleocytoplasmic protein O-fucosylation by SPINDLY regulates diverse developmental processes in plants.Current opinion in structural biology · 2021Review
- Involvement of Arachis hypogaea Jasmonate ZIM domain/TIFY proteins in root nodule symbiosis.Journal of plant research · 2021Article
- Genome-Wide Identification of the Tify Gene Family and Their Expression Profiles in Response to Biotic and Abiotic Stresses in Tea Plants (International journal of molecular sciences · 2020Article
- The GATA transcription factor GNC plays an important role in photosynthesis and growth in poplar.Journal of experimental botany · 2020Article
- The Molecular Basis of JAZ-MYC Coupling, a Protein-Protein Interface Essential for Plant Response to Stressors.Frontiers in plant science · 2020Article
- Functional Characterization of Resistance to Powdery Mildew ofInternational journal of molecular sciences · 2019Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Jasmonate (JA) signalling is mediated by the JASMONATE-ZIM DOMAIN (JAZ) repressor proteins, which are degraded upon JA perception to release downstream responses. The ZIM protein domain is characteristic of the larger TIFY protein family. It is currently unknown if the atypical member TIFY8 is involved in JA signalling. Here we show that the TIFY8 ZIM domain is functional and mediated interaction with PEAPOD proteins and NINJA. TIFY8 interacted with TOPLESS through NINJA and accordingly acted as a transcriptional repressor. TIFY8 expression was inversely correlated with JAZ expression during development and after infection with Pseudomonas syringae. Nevertheless, transgenic lines with altered TIFY8 expression did not show changes in JA sensitivity. Despite the functional ZIM domain, no interaction with JAZ proteins could be found. In contrast, TIFY8 was found in protein complexes involved in regulation of dephosphorylation, deubiquitination and O-linked N-acetylglucosamine modification suggesting an important role in nuclear signal transduction.
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