Evidence map›Paper›PMID 24416293›Full record

ArticlePloS one2014

The role of evidence in the decision-making process of selecting essential medicines in developing countries: the case of Tanzania.

Amani Thomas Mori, Eliangiringa Amos Kaale, Frida Ngalesoni, Ole Frithjof Norheim, Bjarne Robberstad

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Rarely listed essential medicines in 158 national lists.Journal of pharmaceutical policy and practice · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. JAC-antimicrobial resistance · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. A comparison of national essential medicines lists in the Americas.Revista panamericana de salud publica = Pan American journal of public health · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amani Thomas MoriCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway ; School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Eliangiringa Amos KaaleSchool of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Frida NgalesoniCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway ; Ministry of Health and Social Welfare, Dar es Salaam, Tanzania.
Ole Frithjof NorheimCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Bjarne RobberstadCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsufficient access to essential medicines is a major health challenge in developing countries. Despite the importance of Standard Treatment Guidelines and National Essential Medicine Lists in facilitating access to medicines, little is known about how they are updated. This study aims to describe the process of updating the Standard Treatment Guidelines and National Essential Medicine List in Tanzania and further examines the criteria and the underlying evidence used in decision-making.

methodsThis is a qualitative study in which data were collected by in-depth interviews and document reviews. Interviews were conducted with 18 key informants who were involved in updating the Standard Treatment Guidelines and National Essential Medicine List. We used a thematic content approach to analyse the data.

findingsThe Standard Treatment Guidelines and National Essential Medicine List was updated by committees of experts who were recruited mostly from referral hospitals and the Ministry of Health and Social Welfare. Efficacy, safety, availability and affordability were the most frequently utilised criteria in decision-making, although these were largely based on experience rather than evidence. In addition, recommendations from international guidelines and medicine promotions also influenced decision-making. Cost-effectiveness, despite being an important criterion for formulary decisions, was not utilised.

conclusionsRecent decisions about the selection of essential medicines in Tanzania were made by committees of experts who largely used experience and discretionary judgement, leaving evidence with only a limited role in decision-making process. There may be several reasons for the current limited use of evidence in decision-making, but one hypothesis that remains to be explored is whether training experts in evidence-based decision-making would lead to a better and more explicit use of evidence.

Indexed as

Decision MakingDeveloping CountriesAdvertisingCost-Benefit AnalysisDrug IndustryEvidence-Based MedicineExpert TestimonyHealth Services AccessibilityHumansInfantInternationalityPractice Guidelines as TopicSafetyTanzania

Identifiers

PMID24416293
PMCPMC3885598

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.