ArticlePloS one2014
Plant-associated symbiotic Burkholderia species lack hallmark strategies required in mammalian pathogenesis.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed, 173 citations in OpenAlex.
- Regulation of Type VI Secretion Systems of Burkholderia during transition to intracellular lifestyle.EMBO reports · 2026Article
- Genomic Basis of Lifestyle Divergence in Rice-AssociatedInternational journal of molecular sciences · 2026Article
- Secretion systems shaping host-pathogen interactions in Burkholderia species.Applied microbiology and biotechnology · 2026Review
- Identifying phenotypic and genetic traits for assessing pathogenic potential and biocontrol capacity in Burkholderia sensu lato strains.The ISME journal · 2026Article
- Colony morphotype variation inJournal of bacteriology · 2025Review
- The potential of Paraburkholderia species to enhance crop growth.World journal of microbiology & biotechnology · 2025Review
- Article
- Quorum sensing-related activities of beneficial and pathogenic bacteria have important implications for plant and human health.FEMS microbiology ecology · 2024Review
- Human nasal microbiota shifts in healthy and chronic respiratory disease conditions.BMC microbiology · 2024Article
- Wild mushrooms as potential reservoirs of plant pathogenic bacteria: a case study onMicrobiology spectrum · 2024Article
- Comparative Genome Analyses Provide Insight into the Antimicrobial Activity of EndophyticMicroorganisms · 2024Article
- Exploring the comparative genome of rice pathogenFrontiers in plant science · 2024Article
- Prospecting for Zoonotic Pathogens by Using Targeted DNA Enrichment.Emerging infectious diseases · 2023Article
- Quorum sensing activities and genomic insights of plant growth-promoting rhizobacteria isolated from Assam tea.World journal of microbiology & biotechnology · 2023Article
- Potential Biocontrol Activities ofPathogens (Basel, Switzerland) · 2022Article
- Differential Genetic Strategies of Burkholderia vietnamiensis and Paraburkholderia kururiensis for Root Colonization of Oryza sativa subsp.Applied and environmental microbiology · 2022Article
- Paraburkholderia bengalensis sp. nov. isolated from roots of Oryza sativa, IR64.Archives of microbiology · 2022Article
- Multiple Copies ofJournal of bacteriology · 2021Article
- Genome wide association study reveals plant loci controlling heritability of the rhizosphere microbiome.The ISME journal · 2021Article
- Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Burkholderia is a diverse and dynamic genus, containing pathogenic species as well as species that form complex interactions with plants. Pathogenic strains, such as B. pseudomallei and B. mallei, can cause serious disease in mammals, while other Burkholderia strains are opportunistic pathogens, infecting humans or animals with a compromised immune system. Although some of the opportunistic Burkholderia pathogens are known to promote plant growth and even fix nitrogen, the risk of infection to infants, the elderly, and people who are immunocompromised has not only resulted in a restriction on their use, but has also limited the application of non-pathogenic, symbiotic species, several of which nodulate legume roots or have positive effects on plant growth. However, recent phylogenetic analyses have demonstrated that Burkholderia species separate into distinct lineages, suggesting the possibility for safe use of certain symbiotic species in agricultural contexts. A number of environmental strains that promote plant growth or degrade xenobiotics are also included in the symbiotic lineage. Many of these species have the potential to enhance agriculture in areas where fertilizers are not readily available and may serve in the future as inocula for crops growing in soils impacted by climate change. Here we address the pathogenic potential of several of the symbiotic Burkholderia strains using bioinformatics and functional tests. A series of infection experiments using Caenorhabditis elegans and HeLa cells, as well as genomic characterization of pathogenic loci, show that the risk of opportunistic infection by symbiotic strains such as B. tuberum is extremely low.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.