Evidence map›Paper›PMID 24415886›Full record

SynthesisWorld journal of gastroenterology2014

Controlled low central venous pressure reduces blood loss and transfusion requirements in hepatectomy.

Zhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu

Open access · hybridAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 6 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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  5. Central venous pressure and liver resection: a systematic review and meta-analysis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhi LiZhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China.
Yu-Ming SunZhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China.
Fei-Xiang WuZhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China.
Li-Qun YangZhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China.
Zhi-Jie LuZhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China.
Wei-Feng YuZhi Li, Yu-Ming Sun, Fei-Xiang Wu, Li-Qun Yang, Zhi-Jie Lu, Wei-Feng Yu, Department of Anesthesiology, Eastern Hepatobiliary Surgery Hospital, the Second Military Medical University, Shanghai 200438, China.
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the effect of low central venous pressure (LCVP) on blood loss and blood transfusion in patients undergoing hepatectomy.

methodsElectronic databases and bibliography lists were searched for potential articles. A meta-analysis of all randomized controlled trials (RCTs) investigating LCVP in hepatectomy was performed. The following three outcomes were analyzed: blood loss, blood transfusion and duration of operation.

resultsFive RCTs including 283 patients were assessed. Meta-analysis showed that blood loss in the LCVP group was significantly less than that in the control group (MD = -391.95, 95%CI: -559.35--224.56, P < 0.00001). In addition, blood transfusion in the LCVP group was also significantly less than that in the control group (MD = -246.87, 95%CI: -427.06--66.69, P = 0.007). The duration of operation in the LCVP group was significantly shorter than that in the control group (MD = -18.89, 95%CI: -35.18--2.59, P = 0.02). Most studies found no significant difference in renal and liver function between the two groups.

conclusionControlled LCVP is a simple and effective technique to reduce blood loss and blood transfusion during liver resection, and appears to have no detrimental effects on liver and renal function.

Indexed as

Blood TransfusionCentral Venous PressureHepatectomyBlood Loss, SurgicalChi-Square DistributionHumansOdds RatioOperative TimeRisk FactorsTime FactorsTreatment OutcomeBlood lossBlood transfusionHepatectomyLow central venous pressure

Identifiers

PMID24415886
PMCPMC3886023
OpenAlexW2011880258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.