Evidence map›Paper›PMID 24415795›Full record

ArticleJournal of chemical education2013

Solvent-Free Synthesis and Fluorescence of a Thiol-Reactive Sensor for Undergraduate Organic Laboratories.

Anastasia L Patterson, Mary D May, Bryan J Visser, Alexander A Kislukhin, David A Vosburg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of chemical education, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 16 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anastasia L PattersonDepartment of Chemistry, Harvey Mudd College, Claremont, California 91711, United States.
Mary D MayDepartment of Chemistry, Harvey Mudd College, Claremont, California 91711, United States.
Bryan J VisserDepartment of Chemistry, Harvey Mudd College, Claremont, California 91711, United States.
Alexander A KislukhinDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
David A VosburgDepartment of Chemistry, Harvey Mudd College, Claremont, California 91711, United States.
Harvey Mudd College · USScripps Research Institute · US

Funding

Drug Delivery Systems Based on Cleavable OxanorbornadienesF31CA165653 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI KISLUKHIN, ALEXANDER · 2012 to 2012
$25k
NCI NIH HHS F31 CA165653
6 · The paper itself

Abstract

A green organic laboratory experiment was developed in which students synthesize a sensor for thiols using a microscale, solventless Diels-Alder reaction at room temperature or 37 °C. The molecular probe is easily purified by column chromatography in a Pasteur pipet and characterized by thin-layer chromatography and NMR spectroscopy. The thiol-reactive sensor becomes intensely fluorescent upon exposure to thiols from

Indexed as

fluorescence spectroscopygreen chemistryhands-on learninglaboratory instructionmicroscale labNMR Spectroscopyorganic chemistryorganosulfur compoundssecond-year undergraduatesynthesis

Identifiers

PMID24415795
PMCPMC3885416
OpenAlexW1971540507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.