Evidence map›Paper›PMID 24415723›Full record

ReviewJournal of bacteriology2014

Lipoteichoic acids, phosphate-containing polymers in the envelope of gram-positive bacteria.

Olaf Schneewind, Dominique Missiakas

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of bacteriology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 155 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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  6. Exploring Daptomycin Hypersensitivity inInternational journal of molecular sciences · 2025
    Article
  7. Review
  8. Review
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  12. Lipoteichoic Acid fromNutrients · 2024
    Article
  13. Article
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  16. The molecular architecture ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Olaf SchneewindHoward Taylor Ricketts Laboratory, Argonne National Laboratory, Lemont, Illinois, USA, and Department of Microbiology, University of Chicago, Chicago, Illinois, USA.
Dominique Missiakas
Argonne National Laboratory · US

Funding

Vaccines and Therapies Against BotulismU54AI057153 · NIAID · UNIVERSITY OF CHICAGO · PI SHUMAN, HOWARD A · 2003 to 2013
$87.6M
NIAID NIH HHS 1-U54-AI-057153NIAID NIH HHS U54 AI057153
6 · The paper itself

Abstract

Lipoteichoic acids (LTA) are polymers of alternating units of a polyhydroxy alkane, including glycerol and ribitol, and phosphoric acid, joined to form phosphodiester units that are found in the envelope of Gram-positive bacteria. Here we review four different types of LTA that can be distinguished on the basis of their chemical structure and describe recent advances in the biosynthesis pathway for type I LTA, d-alanylated polyglycerol-phosphate linked to di-glucosyl-diacylglycerol. The physiological functions of type I LTA are discussed in the context of inhibitors that block their synthesis and of mutants with discrete synthesis defects. Research on LTA structure and function represents a large frontier that has been investigated in only few Gram-positive bacteria.

Indexed as

Biosynthetic PathwaysCell WallGram-Positive BacteriaLipopolysaccharidesModels, BiologicalModels, MolecularMolecular ConformationTeichoic AcidsLipopolysaccharideslipoteichoic acidTeichoic Acids

Identifiers

PMID24415723
PMCPMC3957714
OpenAlexW2130675566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.