Evidence map›Paper›PMID 24415462›Full record

ArticleWorld journal of microbiology & biotechnology2014

Use of the VNTR typing technique to determine the origin of Mycobacterium tuberculosis strains isolated from Filipino patients in Korea.

Jihye Lee, Thelma E Tupasi, Young Kil Park

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Article in World journal of microbiology & biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Jihye LeeKorean Institute of Tuberculosis, 168-5 Osongsangmyung 4 ro, Osongup, Cheongwongun, Chungbuk, 363-954, Republic of Korea.
Thelma E Tupasi
Young Kil Park

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With increasing international interchange of personnel, international monitoring is necessary to decrease tuberculosis incidence in the world. This study aims to develop a new tool to determine origin of Mycobacterium tuberculosis strains isolated from Filipino patients living in Korea. Thirty-two variable number tandem repeat (VNTR) loci were used for discrimination of 50 Filipino M. tuberculosis strains isolated in the Philippines, 317 Korean strains isolated in Korea, and 8 Filipino strains isolated in Korea. We found that the VNTR loci 0580, 0960, 2531, 2687, 2996, 0802, 2461, 2163a, 4052, 0424, 1955, 2074, 2347, 2401, 3171, 3690, 2372, 3232, and 4156 had different mode among copy numbers or exclusively distinct copy number in VNTR typing between Filipino and Korean M. tuberculosis strains. When these differences of the VNTR loci were applied to 8 Filipino M. tuberculosis strains isolated in Korea, 6 of them revealed Filipino type while 2 of them had Korean type. Using the differences of mode or repeated number of VNTR loci were very useful in distinguishing the Filipino strain from Korean strain.

Indexed as

DNA, BacterialGenetic VariationGenotypeHumansMinisatellite RepeatsMolecular TypingMycobacterium tuberculosisPhilippinesRepublic of KoreaTuberculosis, PulmonaryDNA, Bacterial

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.