ArticleHernia : the journal of hernias and abdominal wall surgery2014
Collagen fibers in the rectus abdominis muscle of cadavers of different age.
Article in Hernia : the journal of hernias and abdominal wall surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Synergistic enhancement of peripheral nerve regeneration using electrospun polylactic acid conduits with leupeptin and methylprednisolone in rats.Biomedical engineering online · 2026Article
- Matrix Metalloproteinases (MMP-2) and Tissue Inhibitors of Metalloproteinases (TIMP-2) in Male Inguinal Hernia Patients at Different Ages.World journal of surgery · 2021Article
- Three-dimensional visualization and measurement of myopectineal orifice in non-inguinal hernia patients.Surgical and radiologic anatomy : SRA · 2020Article
- Cancer invasion into musculature: Mechanics, molecules and implications.Seminars in cell & developmental biology · 2019Review
- Quantification of airway fibrosis in asthma by flow cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018Article
- Correlation between change in muscle excursion and collagen content after tendon rupture and delayed repair.Journal of orthopaedic surgery and research · 2017Article
- Experimental study of inflammatory response and collagen morphometry with different types of meshes.Hernia : the journal of hernias and abdominal wall surgery · 2016Article
- Hiatal hernia and gastroesophageal reflux: Study of collagen in the phrenoesophageal ligament.Surgical endoscopy · 2016Article
- Methylprednisolone microsphere sustained-release membrane inhibits scar formation at the site of peripheral nerve lesion.Neural regeneration research · 2016Article
- Autologous leukocyte-reduced platelet-rich plasma therapy for Achilles tendinopathy induced by collagenase in a rabbit model.Scientific reports · 2016Article
- LINEA ALBA COLLAGEN ASSESSMENT IN MORBIDLY OBESE PATIENTS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2016Article
- Capsular Weakness around Breast Implant: A Non-Recognized Complication.World journal of plastic surgery · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess collagen content and types in the rectus abdominis muscle of cadavers of different ages.
methodsForty fresh adult male cadavers within 24 h of death were obtained from an Institute of Legal Medicine and divided by age at death into Group 1 (mean age, 23.3 years; range, 18-30 years; n = 20) and Group 2 (mean age, 46.2 years; range, 31-60 years; n = 20). From each cadaver, samples of the rectus abdominis muscle measuring 1 cm(2) were collected 3 cm superiorly and 2 cm inferiorly to the umbilicus. Histological sections were prepared and stained with picrosirius red and Masson's trichrome stain for visualization of total collagen fibers, and immunohistochemical analysis was performed to distinguish types I, II, III, IV and V collagen.
resultsNo significant differences in total collagen were found between groups by Masson's trichrome staining. However, picrosirius red staining revealed a significantly greater amount and higher concentration of total collagen and types I and III collagen in Group 1 than in Group 2 (P < 0.05). All but type II collagen were detected by immunohistochemistry in both groups. No significant difference in type IV collagen was found between groups. Type V collagen was detected by immunohistochemistry in both groups, but quantification was not possible due to background staining.
conclusionThe amounts of types I and III collagen in the rectus abdominis muscle were significantly smaller in older subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.