ArticleAge (Dordrecht, Netherlands)2014
Time course of low- and high-volume strength training on neuromuscular adaptations and muscle quality in older women.
Article in Age (Dordrecht, Netherlands), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03272737 (Effect of Low Intensity Strength Training Combined With Moderate Blood Flow Restriction on Muscle Vasodilatation and Arterial Stiffness in Elders With Low Gait Velocity.), which is not on this map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Low Intensity Strength Training Combined With Moderate Blood Flow Restriction on Muscle Vasodilatation and Arterial Stiffness in Elders With Low Gait Velocity.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Influence of Resistance Training Variables to Improve Muscle Mass Outcomes in Sarcopenia: A Systematic Review With Meta-Regressions.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Effects of Resistance Training Volume on Physical Function, Lean Body Mass and Lower-Body Muscle Hypertrophy and Strength in Older Adults: A Systematic Review and Network Meta-analysis of 151 Randomised Trials.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Non invasive techniques for direct muscle quality assessment after exercise intervention in older adults: a systematic review.BMC geriatrics · 2024Pooled it
- Dose-response relationship of resistance training for muscle morphology and strength in elderly cancer patients: A meta-analysis.Frontiers in medicine · 2023Pooled it
- Resistance versus concurrent training with three assigned protein targets in middle-aged and older women: a randomized 2 × 3 factorial trial.Journal of the International Society of Sports Nutrition · 2026Trial
- Resistance training alters body composition in middle-aged women depending on menopause - A 20-week control trial.BMC women's health · 2023Trial
- Resistance training with or without nutritional supplementation showed no influence on muscle thickness in old-institutionalized adults: a secondary analysis of the Vienna Active Ageing Study.European journal of physical and rehabilitation medicine · 2022Trial
- Evaluation of rehabilitation exercise effects by using gradation-based skeletal muscle echo intensity in older individuals: a one-group before-and-after trial study.BMC geriatrics · 2021Trial
- The effects of high intensity interval training on muscle size and quality in overweight and obese adults.Journal of science and medicine in sport · 2018Trial
- Effect of resistance training on muscular strength and indicators of abdominal adiposity, metabolic risk, and inflammation in postmenopausal women: controlled and randomized clinical trial of efficacy of training volume.Age (Dordrecht, Netherlands) · 2016Trial
- Effects of single vs. multiple-set short-term strength training in elderly women.Age (Dordrecht, Netherlands) · 2014Trial
- Single-set versus three-set resistance training in the management of women with patellofemoral pain: A randomized clinical trial.Brazilian journal of physical therapyTrial
- Effects of an exercise program on calf muscle characteristics in patients with Achilles tendinopathy.Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine · 2025Observational
- Muscle quality responses to short-term resistance training volume in older adults: an exploratory clinical trial.Frontiers in aging · 2025Article
- Resistance Exercise Minimal Dose Strategies for Increasing Muscle Strength in the General Population: an Overview.Sports medicine (Auckland, N.Z.) · 2024Review
- Muscle Ultrasound Echo Intensity and Fiber Type Composition in Young Females.Journal of functional morphology and kinesiology · 2024Article
- Effect of subcutaneous adipose tissue and muscle thicknesses on rectus femoris and vastus intermedius ultrasound echo intensities: a cadaver study.Journal of ultrasound · 2023Article
- Effects of Exercise Training on Muscle Quality in Older Individuals: A Systematic Scoping Review with Meta-Analyses.Sports medicine - open · 2023Article
- Relative contribution of neuromuscular activation, muscle size, and muscle quality to maximum strength output of the thigh muscles in young individuals.Physiological reports · 2023Article
- Strength Training Volume to Increase Muscle Mass Responsiveness in Older Individuals: Weekly Sets Based Approach.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the effects of low- and high-volume strength trainings on neuromuscular adaptations of lower- and upper-body muscles in older women after 6 weeks (6WE), 13 weeks (13WE), and 20 weeks (20WE) of training. Healthy older women were assigned to low-volume (LV) or high-volume (HV) training groups. The LV group performed one set of each exercise, while the HV group performed three sets, 2 days/week. Knee extension and elbow flexion one-repetition maximum (1-RM), maximal isometric strength, maximal muscle activation, and muscle thickness (MT) of the lower- and upper-body muscles, as well as lower-body muscle quality (MQ) obtained by ultrasonography, were evaluated. Knee extension and elbow flexion 1-RM improved at all time points for both groups; however, knee extension 1-RM gains were greater for the HV group after 20WE. Maximal isometric strength of the lower body for both groups increased only at 20WE, while upper-body maximal isometric strength increased after 13WE and 20WE. Maximal activation of the lower and upper body for both groups increased only after 20WE. Both groups showed significant increases in MT of their lower and upper body, with greater gains in lower-body MT for the HV group at 20WE. MQ improved in both groups after 13WE and 20WE, whereas the HV group improved more than the LV group at 20WE. These results showed that low- and high-volume trainings have a similar adaptation time course in the muscular function of upper-body muscles. However, high-volume training appears to be more efficient for lower-body muscles after 20 weeks of training.
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Registered trials
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