Evidence map›Paper›PMID 24414064›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2014

Mechanisms of cardiac conduction: a history of revisions.

Rengasayee Veeraraghavan, Robert G Gourdie, Steven Poelzing

Abstract readHistorical ArticleReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Article
  2. Review
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  9. The network of cardiac KNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  10. Concepts of Cardiac Dyssynchrony and Dynamic Approach.Diagnostics (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Fibroblasts, myofibroblasts and cardiac arrhythmias.The journal of cardiovascular aging · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rengasayee VeeraraghavanVirginia Tech Carilion Research Institute, and Center for Heart and Regenerative Medicine, Virginia Polytechnic University, Roanoke, Virginia; and.
Robert G Gourdie
Steven Poelzing

Funding

PATTERNING OF GAP JUNCTION COUPLING IN DEVELOPING HEARTR01HL056728 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GOURDIE, ROBERT G · 1997 to 2021
$5.6M
Role of the Extracellular Space as a Modulator of the Cardiac Gap Junction - Conduction Velocity RelationshipR01HL102298 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI POELZING, STEVEN · 2011 to 2020
$3.9M
An Enabling Technology for Improving Engraftment of Implanted Materials and CellsR01DE019355 · NIDCR · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI YOST, MICHAEL J · 2010 to 2013
$1.4M
NHLBI NIH HHS R01 HL056728NHLBI NIH HHS R01 HL102298NHLBI NIH HHS R01-HL-102298-01A1NHLBI NIH HHS R01-HL-56728-10A2NIDCR NIH HHS R01-1DE019355-01NIDCR NIH HHS R01 DE019355
6 · The paper itself

Abstract

Cardiac conduction is the process by which electrical excitation spreads through the heart, triggering individual myocytes to contract in synchrony. Defects in conduction disrupt synchronous activation and are associated with life-threatening arrhythmias in many pathologies. Therefore, it is scarcely surprising that this phenomenon continues to be the subject of active scientific inquiry. Here we provide a brief review of how the conceptual understanding of conduction has evolved over the last century and highlight recent, potentially paradigm-shifting developments.

Indexed as

Excitation Contraction CouplingHeart Conduction SystemMyocardial ContractionAction PotentialsAnimalsArrhythmias, CardiacHistory, 20th CenturyHistory, 21st CenturyHumansModels, Cardiovascularcardiac conductionephaptic couplinggap junctionsmodelingmyocardium

Identifiers

PMID24414064
PMCPMC3949060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.