ArticleLab on a chip2014
Continuous enrichment of low-abundance cell samples using standing surface acoustic waves (SSAW).
Article in Lab on a chip, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Acoustofluidic multimodal diagnostic system for Alzheimer's disease.Biosensors & bioelectronics · 2022Article
- Surface acoustic wave (SAW) techniques in tissue engineering.Cell and tissue research · 2021Review
- High-Throughput Cell Concentration Using A Piezoelectric Pump in Closed-Loop Viscoelastic Microfluidics.Micromachines · 2021Article
- Acoustofluidic multi-well plates for enrichment of micro/nano particles and cells.Lab on a chip · 2020Article
- Development of Nanoporous AAO Membrane for Nano Filtration Using the Acoustophoresis Method.Sensors (Basel, Switzerland) · 2020Article
- Acoustofluidics-Assisted Engineering of Multifunctional Three-Dimensional Zinc Oxide Nanoarrays.ACS nano · 2020Article
- Intra-droplet particle enrichment in a focused acoustic field.RSC advances · 2020Article
- Airplug-mediated isolation and centralization of single T cells in rectangular microwells for biosensing.Advanced therapeutics · 2020Article
- Cell trapping in Y-junction microchannels: A numerical study of the bifurcation angle effect in inertial microfluidics.Physics of fluids (Woodbury, N.Y. : 1994) · 2019Article
- Design, modeling, and experimental validation of an acoustofluidic platform for nanoscale molecular synthesis and detection.Physics of fluids (Woodbury, N.Y. : 1994) · 2019Article
- Applications of Acoustofluidics in Bioanalytical Chemistry.Analytical chemistry · 2019Article
- Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations.Journal of visualized experiments : JoVE · 2018Article
- Augmented longitudinal acoustic trap for scalable microparticle enrichment.Biomicrofluidics · 2018Article
- Reducing WBC background in cancer cell separation products by negative acoustic contrast particle immuno-acoustophoresis.Analytica chimica acta · 2018Article
- Microfluidic cell concentrator with a reduced-deviation-flow herringbone structure.Biomicrofluidics · 2017Article
- Acoustofluidic waveguides for localized control of acoustic wavefront in microfluidics.Microfluidics and nanofluidics · 2017Article
- Acoustic actuation of bioinspired microswimmers.Lab on a chip · 2017Article
- Enriching Nanoparticles via Acoustofluidics.ACS nano · 2017Article
- Microfluidics cell sample preparation for analysis: Advances in efficient cell enrichment and precise single cell capture.Biomicrofluidics · 2017Review
- Surface Acoustic Waves Grant Superior Spatial Control of Cells Embedded in Hydrogel Fibers.Advanced materials (Deerfield Beach, Fla.) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Cell enrichment is a powerful tool in a variety of cellular studies, especially in applications with low-abundance cell types. In this work, we developed a standing surface acoustic wave (SSAW) based microfluidic device for non-contact, continuous cell enrichment. With a pair of parallel interdigital transducers (IDT) deposited on a piezoelectric substrate, a one-dimensional SSAW field was established along disposable micro-tubing channels, generating numerous pressure nodes (and thus numerous cell-enrichment regions). Our method is able to concentrate highly diluted blood cells by more than 100 fold with a recovery efficiency of up to 99%. Such highly effective cell enrichment was achieved without using sheath flow. The SSAW-based technique presented here is simple, bio-compatible, label-free, and sheath-flow-free. With these advantages, it could be valuable for many biomedical applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.