Evidence map›Paper›PMID 24413763›Full record

ReviewPlant cell reports2014

Transgenic rice endosperm as a bioreactor for molecular pharming.

Jiquan Ou, Zhibin Guo, Jingni Shi, Xianghong Wang, Jingru Liu, Bo Shi, Fengli Guo, Chufu Zhang, Daichnag Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant cell reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Genetic Containment for Molecular Farming.Plants (Basel, Switzerland) · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Plants as Factories for Human Pharmaceuticals: Applications and Challenges.International journal of molecular sciences · 2015
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiquan OuCollege of Life Sciences, State Key Laboratory of Hybrid Rice, Wuhan University, Wuhan, China.
Zhibin Guo
Jingni Shi
Xianghong Wang
Jingru Liu
Bo Shi
Fengli Guo
Chufu Zhang
Daichnag Yang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants provide a promising expression platform for producing recombinant proteins with several advantages in terms of high expression level, lower production cost, scalability, and safety and environment-friendly. Molecular pharming has been recognized as an emerging industry with strategic importance that could play an important role in economic development and healthcare in China. Here, this review represents the significant advances using transgenic rice endosperm as bioreactor to produce various therapeutic recombinant proteins in transgenic rice endosperm and large-scale production of OsrHSA, and discusses the challenges to develop molecular pharming as an emerging industry with strategic importance in China.

Indexed as

BioreactorsEndospermMolecular FarmingOryzaPlants, Genetically ModifiedRecombinant ProteinsRecombinant Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.