Trial reportNature neuroscience2014
Post-study caffeine administration enhances memory consolidation in humans.
Trial report in Nature neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed.
- Post-encoding administration of oxytocin selectively enhances memory consolidation of male faces in females.Proceedings of the National Academy of Sciences of the United States of America · 2026Trial
- Caffeine reduces accuracy in face recognition memory consolidation.Scientific reports · 2025Trial
- Effects of Acute Guarana (Nutrients · 2024Trial
- Cognitive enhancement: Effects of methylphenidate, modafinil, and caffeine on latent memory and resting state functional connectivity in healthy adults.Human brain mapping · 2022Trial
- No Enhancement of 24-Hour Visuomotor Skill Retention by Post-Practice Caffeine Administration.PloS one · 2015Trial
- Boosting long-term memory via wakeful rest: intentional rehearsal is not necessary, consolidation is sufficient.PloS one · 2014Trial
- Investigating the effects of acute caffeine administration on visual search, resistance to distraction, and attentional learning.Cognitive research: principles and implications · 2026Article
- Caffeine expectancy, explicit and implicit memory performance among female nursing students: a placebo-controlled quasi-experimental study.BMC nursing · 2026Article
- The Effect of Caffeine on Various Forms of Synaptic Plasticity in the CA1 Region of Mouse Hippocampal Slices.Biomolecules · 2026Article
- Are future physicians practicing safe caffeine consumption? A structured narrative review of caffeine and energy drink use among medical students.Frontiers in public health · 2026Review
- Upregulation of adenosine AMolecular psychiatry · 2025Article
- Association between coffee consumption and life expectancy: a prospective cohort study from NHANES 2001-2018.Public health nutrition · 2025Article
- Crossmodal semantic congruence and rarity improve episodic memory.Memory & cognition · 2025Article
- Repurposing Caffeine, Metformin, and Furosemide to Target Schizophrenia-Related Impairments in a Triple-Hit Rat Model.International journal of molecular sciences · 2025Article
- Caffeine Consumption Patterns, Health Impacts, and Media Influence: A Narrative Review.Cureus · 2025Review
- Sleep as the Foundation of Brain Health.Seminars in neurology · 2025Review
- Association of caffeine consumption with cerebrospinal fluid biomarkers in mild cognitive impairment and Alzheimer's disease: A BALTAZAR cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- The risk of premature cardiac contractions (PAC/PVC) related to caffeine consumption among healthcare workers: A comprehensive review.Health science reports · 2024Article
- Alcohol and Caffeine Co-Administration Increased Acetylcholinesterase Activity and Inflammatory Cytokines in Sleep-Deprived Rats: Implications for Cognitive Decline and Depressive-Like Manifestations.Sleep science (Sao Paulo, Brazil) · 2024Article
- Comparative study of Saudi and Turkish coffee consumption in Saudi Arabia: insights into sociodemographic factors and caffeine intake.Frontiers in nutrition · 2024Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task. Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval. We conclude that caffeine enhanced consolidation of long-term memories in humans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.