Evidence map›Paper›PMID 24413637›Full record

SynthesisJournal of neurology2014

The effectiveness of physiotherapy for cervical dystonia: a systematic literature review.

Joke De Pauw, Kevin Van der Velden, Jill Meirte, Ulrike Van Daele, Steven Truijen, Patrick Cras, Rudy Mercelis, Willem De Hertogh

2 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03247868 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Multimodal Treatment of Cervical Dystonia With Botulinum Toxin Injections Associated With a Sensory-motor Perceptive Rehabilitation Integrated Approach (SPRInt) Based on Motor Learning Techniques

TypeinterventionalSponsorFondazione Don Carlo Gnocchi ETSRan2016 to 2018Enrolled20ConditionsCervical Dystonia,PrimaryArmsBotulinum Toxin+SPRInt
NCT05502718 narecruitingnot on this mapstarted 2022, after this paper: background citation

Evaluation of the Effect of Personalized Exercise Program on Clinical Findings and Quality of Life of Patients With Cervical Dystonia Who Received Botulinum Toxin Type A Injection

TypeinterventionalSponsorProf. Dr. Şehim KutlayRan2022 to 2025Enrolled34ConditionsDystonia, CervicalArmsStretching and Strengthening Exercises, Breathing and Rhythmic Coordination Exercises
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Sensorimotor Perceptive Rehabilitation Integrated (SPRInt) program: exercises with augmented movement feedback associated to botulinum neurotoxin in idiopathic cervical dystonia-an observational study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Trial
  6. Optimal physiotherapy management strategies for cervical dystonia: an international Delphi study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  7. Review
  8. Brain network pathophysiology in dystonia.Dystonia (Lausanne, Switzerland) · 2025
    Article
  9. Article
  10. Review
  11. Genetic Update and Treatment for Dystonia.International journal of molecular sciences · 2024
    Review
  12. [Pain and cervical dystonia].Schmerz (Berlin, Germany) · 2024
    Review
  13. Article
  14. Impact of Physiotherapy in the Treatment of Pain in Cervical Dystonia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Dystonia.BMJ (Clinical research ed.) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joke De PauwDepartment of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium, joke.depauw@uantwerpen.be.
Kevin Van der Velden
Jill Meirte
Ulrike Van Daele
Steven Truijen
Patrick Cras
Rudy Mercelis
Willem De Hertogh
University of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical dystonia is a form of adult-onset, focal dystonia characterized by involuntary contractions of the neck muscles, leading to a disabling, abnormal head posture. CD has a great impact on the activities of daily living (ADL) and quality of life. Currently, the most widely used and recommended first line treatment is botulinum toxin type A (BoNT/A) injections. Physiotherapy is a potentially useful adjuvant, but little is known about its effectiveness. Consequently, our objective was to investigate the effectiveness of physiotherapy alone or as an adjuvant treatment to BoNT/A injections in cervical dystonia (CD) by means of a systematic literature review. Two online databases, PubMed and Web of Science, were searched for articles describing the effectiveness of physiotherapy treatment for CD. After screening, based on predefined in- and exclusion criteria, 16 studies were retained. Their methodological quality was assessed according to Cochrane guidelines. The methodological quality of most studies was low. Examples of shortcomings are small sample sizes, lack of randomization or blinding, and diversity in therapeutic techniques and outcome measures. Only seven studies were clinical trials; the remaining were either case reports or case series. The reported physiotherapy treatments included EMG biofeedback training, muscular elongation, postural exercises and electrotherapy. Improvements in head position, pain, cervical range of motion, quality of life and ADL have been reported, which is promising. Cautious interpretation on the effectiveness of physiotherapy as an adjuvant therapy is required. Before firm conclusions can be drawn, additional high quality trials are needed.

Indexed as

Physical Therapy ModalitiesActivities of Daily LivingDatabases, BibliographicHumansTorticollis

Identifiers

PMID24413637
OpenAlexW2162367116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.