Evidence map›Paper›PMID 24413320›Full record

ArticleLeukemia2014

Whole-exome sequencing of polycythemia vera revealed novel driver genes and somatic mutation shared by T cells and granulocytes.

L Wang, S I Swierczek, J Drummond, K Hickman, S J Kim, K Walker, H Doddapaneni, D M Muzny, R A Gibbs, D A Wheeler and 1 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Second Cancer Onset in Myeloproliferative Neoplasms: What, When, Why?International journal of molecular sciences · 2022
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Polycythemia Vera.Current treatment options in oncology · 2018
    Review
  9. Familial MPN Predisposition.Current hematologic malignancy reports · 2017
    Review
  10. Article
  11. Article
  12. Article
  13. Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

L WangHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
S I SwierczekDivision of Hematology, The University of Utah School of Medicine and VAH, Salt Lake City, UT 84132, USA.
J DrummondHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000000226125958
K HickmanDivision of Hematology, The University of Utah School of Medicine and VAH, Salt Lake City, UT 84132, USA.
S J KimDivision of Hematology, The University of Utah School of Medicine and VAH, Salt Lake City, UT 84132, USA.
K WalkerHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
H DoddapaneniHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
D M MuznyHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
R A GibbsHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
D A WheelerHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
J T PrchalDivision of Hematology, The University of Utah School of Medicine and VAH, Salt Lake City, UT 84132, USA.

Funding

The Human Genome Sequencing CenterU54HG003273 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2004 to 2015
$341.3M
Tissue BankP01CA108671 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Ronald Hoffman · 2006 to 2026
$82.0M
NCI NIH HHS P01 CA108671NCI NIH HHS P01CA108671NHGRI NIH HHS 5U54HG003273NHGRI NIH HHS U54 HG003273
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ExomeMutationDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AGranulocytesHumansJanus Kinase 2Polycythemia VeraRepressor ProteinsSequence Analysis, DNAT-LymphocytesASXL1 protein, humanDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanJAK2 protein, humanJanus Kinase 2Repressor Proteins

Identifiers

PMID24413320
PMCPMC4532385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.