Evidence map›Paper›PMID 24412282›Full record

ArticleOphthalmology2014

Gonioscopy-assisted transluminal trabeculotomy, ab interno trabeculotomy: technique report and preliminary results.

Davinder S Grover, David G Godfrey, Oluwatosin Smith, William J Feuer, Ildamaris Montes de Oca, Ronald L Fellman

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07542522 (Outcome of Gonioscopy-Assisted Transluminal Trabeculotomy in Glaucoma Following Pediatric Cataract Surgery. A Prospective Interventional Case Series.), which is not on this map. Cited by 188 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed, 2 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07542522 nacompletednot on this mapstarted 2024, after this paper: background citation

Outcome of Gonioscopy-Assisted Transluminal Trabeculotomy in Glaucoma Following Pediatric Cataract Surgery. A Prospective Interventional Case Series.

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled30ConditionsGlaucoma Following Pediatric Cataract SurgeryArmsgonioscopy assissted transluminal trabeculotomy
3 · Its place in the literature

Who cites it

188 citing papers in PubMed, 2 syntheses or guidelines pooled it, 402 citations in OpenAlex.

  1. Minimally invasive trabecular meshwork surgery for open-angle glaucoma.The Cochrane database of systematic reviews · 2026
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  8. Safety of gonioscopy-assisted transluminal trabeculotomy without antithrombotic discontinuation versus no antithrombotic therapy: a large cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  9. Efficacy and safety of gonioscopy-assisted transluminal trabeculotomy in glaucoma secondary to fuchs uveitis syndrome: a multicenter study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  10. Comparative efficacy of glaucoma drainage device versus ab-interno trabeculotomy in vitrectomized eyes with secondary glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  11. Intraocular pressure spikes after trabecular meshwork strip peeling during hemi-GATT.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Davinder S GroverGlaucoma Associates of Texas, Dallas, Texas. Electronic address: dgrover@glaucomaassociates.com.
David G GodfreyGlaucoma Associates of Texas, Dallas, Texas.
Oluwatosin SmithGlaucoma Associates of Texas, Dallas, Texas.
William J FeuerBascom Palmer Eye Institute, University of Miami, Miami, Florida.
Ildamaris Montes de OcaUnidad Oftalmologica Montego c.a, Barquisimeto, Venezuela.
Ronald L FellmanGlaucoma Associates of Texas, Dallas, Texas.
Glaucoma Associates of Texas · USMiami Dermatology and Laser Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo introduce a minimally invasive, ab interno approach to a circumferential 360-degree trabeculotomy and to report the preliminary results.

designRetrospective, noncomparative cases series.

participantsEighty-five eyes of 85 consecutive patients who sought treatment at Glaucoma Associates of Texas with uncontrolled open-angle glaucoma and underwent gonioscopy-assisted transluminal trabeculotomy (GATT) for whom there was at least 6 months of follow-up data.

methodsRetrospective chart review of patients who underwent GATT by 4 of the authors (D.S.G., D.G.G., O.S., R.L.F.) between October 2011 and October 2012. The surgery was performed in adults with various open-angle glaucomas.

main outcome measuresIntraocular pressure (IOP), glaucoma medications, visual acuity, and intraoperative as well as postoperative complications.

resultsEighty-five patients with an age range of 24 to 88 years underwent GATT with at least 6 months of follow-up. In 57 patients with primary open-angle glaucoma, the IOP decreased by 7.7 mmHg (standard deviation [SD], 6.2 mm Hg; 30.0% [SD, 22.7%]) with an average decrease in glaucoma medications of 0.9 (SD, 1.3) at 6 months. In this group, the IOP decreased by 11.1 mmHg (SD, 6.1 mmHg; 39.8% [SD, 16.0%]) with 1.1 fewer glaucoma medications at 12 months. In the secondary glaucoma group of 28 patients, IOP decreased by 17.2 mmHg (SD, 10.8 mmHg; 52.7% [SD, 15.8%]) with an average of 2.2 fewer glaucoma medications at 6 months. In this group, the IOP decreased by 19.9 mmHg (SD, 10.2 mmHg; 56.8% [SD, 17.4%]) with an average of 1.9 fewer medications (SD, 2.1) at 12 months. Treatment was considered to have failed in 9% (8/85) of patients because of the need for further glaucoma surgery. The cumulative proportion of failure at 1 year ranged from 0.1 to 0.32, depending on the group. Lens status or concurrent cataract surgery did not have a statistically significant effect on IOP in eyes that underwent GATT at either 6 or 12 months (P > 0.35). The most common complication was transient hyphema, seen in 30% of patients at the 1-week visit.

conclusionsThe preliminary results and safety profile for GATT, a minimally invasive circumferential trabeculotomy, are promising and at least equivalent to previously published results for ab externo trabeculotomy.

Indexed as

AdultAgedAged, 80 and overAntihypertensive AgentsFemaleFollow-Up StudiesGlaucoma, Open-AngleGonioscopyHumansIntraocular PressureIntraoperative ComplicationsMaleMiddle AgedMinimally Invasive Surgical ProceduresPostoperative ComplicationsRetrospective StudiesAntihypertensive Agents

Identifiers

PMID24412282
OpenAlexW2045381608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.