ArticleCurrent biology : CB2014
Plasmodium falciparum infection increases Anopheles gambiae attraction to nectar sources and sugar uptake.
Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Avian malaria and the overlooked metabolic pathways underlying mosquitoRoyal Society open science · 2025Article
- Insights into malaria vectors-plant interaction in a dryland ecosystem.Scientific reports · 2024Article
- The influence of oviposition status on measures of transmission potential in malaria-infected mosquitoes depends on sugar availability.Parasites & vectors · 2024Article
- Effects of Carbohydrate Intake onInsects · 2024Article
- Mosquito ageing modulates the development, virulence and transmission potential of pathogens.Proceedings. Biological sciences · 2024Article
- Infection burdens and virulence under heat stress: ecological and evolutionary considerations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Adipokinetic hormone signaling in the malaria vector Anopheles gambiae facilitates Plasmodium falciparum sporogony.Communications biology · 2023Article
- A comparison of the attractiveness of flowering plant blossoms versus attractive targeted sugar baits (ATSBs) in western Kenya.PloS one · 2023Article
- Contemporary exploitation of natural products for arthropod-borne pathogen transmission-blocking interventions.Parasites & vectors · 2022Review
- Rapamycin inhibits pathogen transmission in mosquitoes by promoting immune activation.PLoS pathogens · 2021Article
- Modulation of odour-guided behaviour in mosquitoes.Cell and tissue research · 2021Review
- Unveiling the Sugary Secrets ofFrontiers in microbiology · 2021Review
- Olfaction in Anopheles mosquitoes.Chemical senses · 2021Review
- Supplementing Blood Diet With Plant Nectar Enhances Egg Fertility inFrontiers in physiology · 2021Article
- Review
- Vector competence and feeding-excretion behavior of Triatoma rubrovaria (Blanchard, 1843) (Hemiptera: Reduviidae) infected with Trypanosoma cruzi TcVI.PLoS neglected tropical diseases · 2020Article
- The consequences of Brugia malayi infection on the flight and energy resources of Aedes aegypti mosquitoes.Scientific reports · 2019Article
- Comprehensive and Durable Modulation of Growth, Development, Lifespan and Fecundity inFrontiers in microbiology · 2019Article
- Unexpectedly high Plasmodium sporozoite rate associated with low human blood index in Anopheles coluzzii from a LLIN-protected village in Burkina Faso.Scientific reports · 2018Article
- Keeping track of mosquitoes: a review of tools to track, record and analyse mosquito flight.Parasites & vectors · 2018Review
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Authors and funding
6 authors.
Funding
Abstract
Plasmodium parasites are known to manipulate the behavior of their vectors so as to enhance transmission. From an evolutionary standpoint, behavior manipulation by the parasite should expose the vector to limited risk of early mortality while ensuring sufficient energy supply for both it and the vector. However, it is unknown whether this vector manipulation also affects vector-plant interaction and sugar uptake. Here, we show that the attraction of Anopheles gambiae s.s. to plant odors increased by 30% and 24% after infection with the oocyst and sporozoite stages of Plasmodium falciparum, respectively, while probing activity increased by 77% and 80%, respectively, when the vectors were infected with the two stages of the parasite. Our data also reveal an increased sugar uptake at the oocyst stage that decreased at the sporozoite stage of infection compared to uninfected An. gambiae, with depletion of lipid reserves at the sporozoite stage. These results point to a possible physiological adjustment by An. gambiae to P. falciparum infection or behavior manipulation of An. gambiae by P. falciparum to enhance transmission. We conclude that the nectar-seeking behavior of P. falciparum-infected An. gambiae appears to be modified in a manner governed by the vector's fight for survival and the parasite's need to advance its transmission.
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