ArticleCurrent biology : CB2014
Top-down response suppression mitigates action tendencies triggered by a motivating stimulus.
Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 62 citations in OpenAlex.
- Observational
- Drug cue enhances response conflict and reduces conflict adaptation in methamphetamine addiction.Psychological research · 2026Article
- Neural dynamics underlying coordination between training-induced habitual and goal-directed responses.Cognitive, affective & behavioral neuroscience · 2025Article
- Article
- Reward signals in the motor cortex: from biology to neurotechnology.Nature communications · 2025Review
- Hypocretin-1 receptor antagonism improves inhibitory control during the Go/No-Go task in highly motivated, impulsive male mice.Psychopharmacology · 2024Article
- Enhanced Pavlovian-to-instrumental transfer in internet gaming disorder.Journal of behavioral addictions · 2023Article
- The influence of associative reward learning on motor inhibition.Psychological research · 2022Article
- Dorsomedial prefrontal cortex activation disrupts Pavlovian incentive motivation.Frontiers in behavioral neuroscience · 2022Article
- The past, present, and future of selection history.Neuroscience and biobehavioral reviews · 2021Review
- Working memory load reduces corticospinal suppression to former go and trained no-go cues.Scientific reports · 2021Article
- The effect of motor engagement on memory: Testing a motor-induced encoding account.Memory & cognition · 2021Article
- Influence of post-stroke fatigue on reaction times and corticospinal excitability during movement preparation.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Observational
- An Adaptation of Pavlovian-to-Instrumental Transfer (PIT) Methodology to Examine the Energizing Effects of Reward-Predicting Cues on Behavior in Young Adults.Frontiers in psychology · 2020Article
- Response Inhibition and Binge Drinking During Transition to University: An fMRI Study.Frontiers in psychiatry · 2020Article
- Neural correlates of reward-related response tendencies in an equiprobable Go/NoGo task.Cognitive, affective & behavioral neuroscience · 2019Article
- Motor Cortex Excitability Reflects the Subjective Value of Reward and Mediates Its Effects on Incentive-Motivated Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Interactions between incentive valence and action information in a cued approach-avoidance task.Psychological research · 2019Article
- Reward improves response inhibition by enhancing attentional capture.Social cognitive and affective neuroscience · 2019Article
- Motor Preparation for Action Inhibition: A Review of Single Pulse TMS Studies Using the Go/NoGo Paradigm.Frontiers in psychology · 2019Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Motivating stimuli provoke action tendencies that sometimes lead to unwanted behavior (e.g., eating chocolate when trying to diet). Implementing control over these provocations is essential to healthy functioning; however, few laboratory-based models of such control exist. Here we developed a novel task in which thirsty human subjects made instrumental responses to obtain a juice reward (Go trials) or were required to withhold responding (NoGo trials) in the presence of a rewarded (CS+) or unrewarded (CS-) conditioned stimulus. For Go trials, single-pulse transcranial magnetic stimulation revealed a rapid increase in motor activity for CS+ versus CS-, preceding more vigorous instrumental responding. Critically, successful NoGo trials resulted in suppression of motor activity for CS+, but not CS-. Moreover, while there was broad excitation in the hand muscles in Go trials, suppression in NoGo trials was selective to the effector that could obtain reward. These results show that response suppression can be triggered by a motivational stimulus, thus providing a richer model of self-control than classic cognitive psychology paradigms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.