Evidence map›Paper›PMID 24411650›Full record

ArticleLancet (London, England)2014

Increasing value and reducing waste: addressing inaccessible research.

An-Wen Chan, Fujian Song, Andrew Vickers, Tom Jefferson, Kay Dickersin, Peter C Gøtzsche, Harlan M Krumholz, Davina Ghersi, H Bart van der Worp

Abstract read
In one paragraph

Article in Lancet (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 366 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
366citing papers in PubMed, 19 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

366 citing papers in PubMed, 19 syntheses or guidelines pooled it.

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  8. Knowledge translation concerns for the CONSORT-PRO extension reporting guidance: a review of reviews.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  9. Reducing waste in collection of quality-of-life data through better reporting: a case study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  10. Reporting quality of surgical randomised controlled trials in head and neck cancer: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
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306 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

An-Wen ChanWomen's College Research Institute, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, ON, Canada. Electronic address: anwen.chan@utoronto.ca.
Fujian SongNorwich Medical School, Faculty of Medicine and Health Science, University of East Anglia, Norwich, UK.
Andrew VickersDepartment of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Tom JeffersonThe Cochrane Collaboration, Rome, Italy.
Kay DickersinCenter for Clinical Trials, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Peter C GøtzscheNordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.
Harlan M KrumholzSection of Cardiovascular Medicine and the Robert Wood Johnson Foundation Clinical Scholars Program, Department of Medicine, Yale School of Medicine, Yale University, New Haven, CT, USA; Department of Health Policy and Management, Yale School of Public Health, Yale University, New Haven, CT, USA; Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT, USA.
Davina GhersiResearch Translation Branch, National Health and Medical Research Council, Canberra, ACT, Australia.
H Bart van der WorpDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
SPORE In Prostate CancerP50CA092629 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Yu Chen, MICHAEL J MORRIS · 2001 to 2026
$63.0M
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA092629NCI NIH HHS P50-CA92629
6 · The paper itself

Abstract

The methods and results of health research are documented in study protocols, full study reports (detailing all analyses), journal reports, and participant-level datasets. However, protocols, full study reports, and participant-level datasets are rarely available, and journal reports are available for only half of all studies and are plagued by selective reporting of methods and results. Furthermore, information provided in study protocols and reports varies in quality and is often incomplete. When full information about studies is inaccessible, billions of dollars in investment are wasted, bias is introduced, and research and care of patients are detrimentally affected. To help to improve this situation at a systemic level, three main actions are warranted. First, academic institutions and funders should reward investigators who fully disseminate their research protocols, reports, and participant-level datasets. Second, standards for the content of protocols and full study reports and for data sharing practices should be rigorously developed and adopted for all types of health research. Finally, journals, funders, sponsors, research ethics committees, regulators, and legislators should endorse and enforce policies supporting study registration and wide availability of journal reports, full study reports, and participant-level datasets.

Indexed as

Information DisseminationAccess to InformationBiomedical ResearchClinical Trials as TopicHumansPeriodicals as TopicPublication BiasPublishingResearch Design

Identifiers

PMID24411650
PMCPMC4533904

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.