Evidence map›Paper›PMID 24411207›Full record

ArticleInternational journal of cardiology2014

Clinical research priorities in adult congenital heart disease.

Timothy Cotts, Paul Khairy, Alexander R Opotowsky, Anitha S John, Anne Marie Valente, Ali N Zaidi, Stephen C Cook, Jamil Aboulhosn, Jennifer Grando Ting, Michelle Gurvitz and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Impact of pulmonary valve replacement on left and right ventricular function using strain analysis, in children with repaired tetralogy of Fallot.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Design and Implementation of a Prospective Adult Congenital Heart Disease Biobank.World journal for pediatric & congenital heart surgery · 2016
    Article
  8. Transition from paediatric to adult care of adolescent patients with congenital heart disease: a pathway to optimal care.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2016
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 15 institutions in 2 countries.

Timothy CottsDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, United States; Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address: cottstim@umich.edu.
Paul KhairyMontreal Heart Institute, Université de Montréal, Montreal, Canada.
Alexander R OpotowskyBoston Children's Hospital, Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Anitha S JohnDivision of Cardiology, Children's National Medical Center, Washington, D.C., United States.
Anne Marie ValenteBoston Children's Hospital, Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Ali N ZaidiColumbus Ohio Adult Congenital Heart Disease Program, The Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, United States; Department of Pediatrics, The Ohio State University, Columbus, OH, United States; Department of Internal Medicine, The Ohio State University, Columbus, OH, United States.
Stephen C CookDepartment of Pediatrics, Heart Institute, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States.
Jamil AboulhosnDepartment of Internal Medicine, University of California, Los Angeles, CA, United States.
Jennifer Grando TingHeart & Vascular Institute, Hershey Medical Center, Pennsylvania State University, Hershey, PA, United States.
Michelle GurvitzBoston Children's Hospital, Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Michael J LandzbergBoston Children's Hospital, Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Amy VerstappenAdult Congenital Heart Association, Philadelphia, PA, United States.
Joseph KayDepartment of Internal Medicine, University of Colorado, Denver, United States; Department of Pediatrics, University of Colorado, Denver, United States.
Michael EaringDepartment of Internal Medicine, Medical College of Wisconsin, Milwaukee, WI, United States; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States.
Wayne FranklinDepartment of Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, United States; Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, United States.
Brian KogonDivision of Cardiothoracic Surgery, Emory University, Atlanta, GA, United States.
Craig S BrobergKnight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, United States.
Alliance for Adult Research in Congenital Cardiology (AARCC)
Harvard University · USAdult Congenital Heart Association · USBaylor College of Medicine · USBrigham and Women's Hospital · USChildren's Hospital of Pittsburgh · USChildren's National · USEmory University · USMedical College of Wisconsin · USNationwide Children's Hospital · USOregon Health & Science University · USPenn State Milton S. Hershey Medical Center · USUniversité de Montréal · CAUniversity of California, Los Angeles · USUniversity of Colorado Denver · USUniversity of Michigan–Ann Arbor · US

Funding

REACH: Research Empowerment for Adult Congenital HeartsRC4HL104831 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SAHN, DAVID J. · 2010 to 2010
$996k
NHLBI NIH HHS RC4 HL104831
6 · The paper itself

Abstract

backgroundAdult congenital heart disease (ACHD) clinicians are hampered by the paucity of data to inform clinical decision-making. The objective of this study was to identify priorities for clinical research in ACHD.

methodsA list of 45 research questions was developed by the Alliance for Adult Research in Congenital Cardiology (AARCC), compiled into a survey, and administered to ACHD providers. Patient input was sought via the Adult Congenital Heart Association at community meetings and online forums. The 25 top questions were sent to ACHD providers worldwide via an online survey. Each question was ranked based on perceived priority and weighted based on time spent in ACHD care. The top 10 topics identified are presented and discussed.

resultsThe final online survey yielded 139 responses. Top priority questions related to tetralogy of Fallot (timing of pulmonary valve replacement and criteria for primary prevention ICDs), patients with systemic right ventricles (determining the optimal echocardiographic techniques for measuring right ventricular function, and indications for tricuspid valve replacement and primary prevention ICDs), and single ventricle/Fontan patients (role of pulmonary vasodilators, optimal anticoagulation, medical therapy for preservation of ventricular function, treatment for protein losing enteropathy). In addition, establishing criteria to refer ACHD patients for cardiac transplantation was deemed a priority.

conclusionsThe ACHD field is in need of prospective research to address fundamental clinical questions. It is hoped that this methodical consultation process will inform researchers and funding organizations about clinical research topics deemed to be of high priority.

Indexed as

AdultBiomedical ResearchCongresses as TopicData CollectionFemaleHeart Defects, CongenitalHumansMalePhysiciansProspective StudiesCongenital heart diseaseFontan procedureSurveyTetralogy of FallotTransposition of the great arteries

Identifiers

PMID24411207
PMCPMC3940155
OpenAlexW2058365561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.