ArticleVirology journal2014
Myocarditis, hepatitis, and pancreatitis in a patient with coxsackievirus A4 infection: a case report.
Article in Virology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Viral-Attributed Acute Pancreatitis: A Systematic Review.Digestive diseases and sciences · 2021Pooled it
- Advancing Myocarditis Research: Evaluating Animal Models for Enhanced Pathophysiological Insights.Current cardiology reports · 2025Review
- Case report: A case of acute pancreatitis with myocarditis and thyrotoxicosis.Frontiers in cardiovascular medicine · 2025Article
- A case of biopsy-proven inflammatory dilated cardiomyopathy following heterologous mRNA-1273 third-dose immunization.ESC heart failure · 2024Article
- Changing Epidemiology of Hand, Foot, and Mouth Disease Causative Agents and Contributing Factors.The American journal of tropical medicine and hygiene · 2024Review
- Global landscape of coxsackieviruses in human health.Virus research · 2024Review
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- Article
- Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release.Frontiers in pharmacology · 2023Article
- The possible role of viral infections in acute pancreatitis: a review of literature.Gastroenterology and hepatology from bed to bench · 2023Review
- An outbreak of a novel recombinant Coxsackievirus A4 in a kindergarten, Shandong province, China, 2021.Emerging microbes & infections · 2022Article
- Viral meningitis: an overview.Archives of virology · 2021Review
- A rare case of fulminant type 1 diabetes mellitus accompanied by both acute pancreatitis and myocarditis - case report.BMC endocrine disorders · 2020Article
- Emerging recombination of the C2 sub-genotype of HFMD-associated CV-A4 is persistently and extensively circulating in China.Scientific reports · 2019Article
- Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man.Texas Heart Institute journal · 2019Article
- A neonatal murine model of coxsackievirus A4 infection for evaluation of vaccines and antiviral drugs.Emerging microbes & infections · 2019Article
- A case report of myocarditis combined with hepatitis caused by herpes simplex virus.BMC cardiovascular disorders · 2018Article
- Pancreatitis and myocarditis coexistence due to infection by Coxsackie B1 and B4 viruses.Clinical case reports · 2018Article
- Acute pancreatitis in hand, foot and mouth disease caused by Coxsackievirus A16: case report.Korean journal of pediatrics · 2017Article
- Echovirus 6 Infects Human Exocrine and Endocrine Pancreatic Cells and Induces Pro-Inflammatory Innate Immune Response.Viruses · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viral myocarditis presents with various symptoms, including fatal arrhythmia and cardiogenic shock, and may develop chronic myocarditis and dilated cardiomyopathy in some patients. We report here a case of viral myocarditis with liver dysfunction and pancreatitis. A 63-year-old man was admitted to our hospital with dyspnea. The initial investigation showed pulmonary congestion, complete atrioventricular block, left ventricular dysfunction, elevated serum troponin I, and elevated liver enzyme levels. He developed pancreatitis five days after admission. Further investigation revealed a high antibody titer against coxsackievirus A4. The patient's left ventricular dysfunction, pancreatitis, and liver dysfunction had resolved by day 14, but his troponin I levels remained high, and an endomyocardial biopsy showed T-lymphocyte infiltration of the myocardium, confirming acute myocarditis. The patient underwent radical low anterior resection five weeks after admission for advanced rectal cancer found incidentally. His serum troponin I and plasma brain natriuretic peptide levels normalized six months after admission. He has now been followed-up for two years, and his left ventricular ejection fraction is stable.This is the first report of an adult with myocarditis and pancreatitis attributed to coxsackievirus A4. Combined myocarditis and pancreatitis arising from coxsackievirus infection is rare. This patient's clinical course suggests that changes in his immune response associated with his rectal cancer contributed to the amelioration of his viral myocarditis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.