ArticleBMC cardiovascular disorders2014
Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study.
Article in BMC cardiovascular disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Acute Psychological Stress and Pulse Wave Velocity: Meta-Analysis and Recommendations for Future Research.Psychophysiology · 2025Pooled it
- Brachial-ankle pulse wave velocity and prognosis in patients with atherosclerotic cardiovascular disease: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Pooled it
- Association of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review.Journal of atherosclerosis and thrombosis · 2017Pooled it
- Trial
- Decreased heritability and emergence of novel genetic effects on pulse wave velocity from youth to young adulthood.Scientific reports · 2021Trial
- Comparison of Carotid-Femoral and Brachial-Ankle Pulse-Wave Velocity in Association With Target Organ Damage in the Community-Dwelling Elderly Chinese: The Northern Shanghai Study.Journal of the American Heart Association · 2017Trial
- Association of LDL protein cargo with segmental pulse wave velocity in older adults in the atherosclerosis risk in communities study.Frontiers in aging · 2026Article
- Acute effects of low-intensity one-legged electrical muscle stimulation on arterial stiffness in experimental and control limbs.Scientific reports · 2024Article
- Early Atherosclerosis in Familial Hypercholesterolemia Patients: Significance of Vascular Markers for Risk Stratification.Journal of cardiovascular development and disease · 2024Article
- Interaction between body mass index and blood pressure on the risk of vascular stiffness : A community-based cross-sectional study and implications for nursing.International journal of nursing sciences · 2023Article
- Brachial-ankle pulse wave velocity increasing with heart rate accelerates.Frontiers in cardiovascular medicine · 2023Article
- Associations of lower-limb atherosclerosis and arteriosclerosis with cardiovascular risk factors and disease in older adults: The Atherosclerosis Risk in Communities (ARIC) study.Atherosclerosis · 2022Article
- Aortic Area as an Indicator of Subclinical Cardiovascular Disease.The open cardiovascular medicine journal · 2022Article
- Determination of aortic pulse transit time based on waveform decomposition of radial pressure wave.Scientific reports · 2021Article
- Comparison between estimated and brachial-ankle pulse wave velocity for cardiovascular and overall mortality prediction.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Clinical significance of central systolic blood pressure in LV diastolic dysfunction and CV mortality.PloS one · 2021Observational
- Associations between carotid-femoral and heart-femoral pulse wave velocity in older adults: the Atherosclerosis Risk In Communities study.Journal of hypertension · 2020Article
- Acute Changes in Carotid-Femoral Pulse-Wave Velocity Are Tracked by Heart-Femoral Pulse-Wave Velocity.Frontiers in cardiovascular medicine · 2020Article
- Association of Low Serum l-Carnitine Levels with Peripheral Arterial Stiffness in Patients Who Undergo Kidney Transplantation.Nutrients · 2019Article
- Comparative effect of statins and types of physical exercise on arterial stiffness: Protocol for network meta-analysis.Medicine · 2019Article
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Authors and funding
15 authors.
Funding
Abstract
backgroundBoth carotid-femoral (cf) pulse wave velocity (PWV) and brachial-ankle (ba) PWV employ arterial sites that are not consistent with the path of blood flow. Few previous studies have reported the differential characteristics between cfPWV and baPWV by simultaneously comparing these with measures of pure central (aorta) and peripheral (leg) arterial stiffness, i.e., heart-femoral (hf) PWV and femoral-ankle (fa) PWV in healthy populations. We aimed to identify the degree to which these commonly used measures of cfPWV and baPWV correlate with hfPWV and faPWV, respectively, and to evaluate whether both cfPWV and baPWV are consistent with either hfPWV or faPWV in their associations with cardiovascular (CV) risk factors.
methodsA population-based sample of healthy 784 men aged 40-49 (202 white Americans, 68 African Americans, 202 Japanese-Americans, and 282 Koreans) was examined in this cross-sectional study. Four regional PWVs were simultaneously measured by an automated tonometry/plethysmography system.
resultscfPWV correlated strongly with hfPWV (r = .81, P < .001), but weakly with faPWV (r = .12, P = .001). baPWV correlated moderately with both hfPWV (r = .47, P < .001) and faPWV (r = .62, P < .001). After stepwise regression analyses with adjustments for race, cfPWV shared common significant correlates with both hfPWV and faPWV: systolic blood pressure (BP) and body mass index (BMI). However, BMI was positively associated with hfPWV and cfPWV, and negatively associated with faPWV. baPWV shared common significant correlates with hfPWV: age and systolic BP. baPWV also shared the following correlates with faPWV: systolic BP, triglycerides, and current smoking.
conclusionsAmong healthy men aged 40 - 49, cfPWV correlated strongly with central PWV, and baPWV correlated with both central and peripheral PWVs. Of the CV risk factors, systolic BP was uniformly associated with all the regional PWVs. In the associations with factors other than systolic BP, cfPWV was consistent with central PWV, while baPWV was consistent with both central and peripheral PWVs.
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