ArticleAIDS care2014
Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse.
Article in AIDS care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Childhood Sexual Trauma and Antiretroviral Therapy Adherence: A Mixed-Methods Systematic Review.AIDS and behavior · 2021Pooled it
- Behavioral Interventions Targeting Alcohol Use Among People Living with HIV/AIDS: A Systematic Review and Meta-Analysis.AIDS and behavior · 2017Pooled it
- Exercise to Prevent Accelerated Vascular Aging in People Living With HIV.Circulation research · 2024Review
- Childhood sexual abuse and antiretroviral therapy adherence among older adults living with HIV: a mixed methods study.AIDS care · 2024Article
- Article
- Bidirectional Violence Is Associated with Poor Engagement in HIV Care and Treatment in Malawian Couples.Journal of interpersonal violence · 2022Article
- Age and Sex Disparities in Sexual Trauma, Depressive Symptoms, and Antiretroviral Adherence Among People Living with HIV in the Deep South: A Mediation Analysis.Archives of sexual behavior · 2021Article
- Application of the Consolidated Framework for Implementation Research to Facilitate Delivery of Trauma-Informed HIV Care.Ethnicity & disease · 2021Article
- ART uptake and adherence among women who use drugs globally: A scoping review.Drug and alcohol dependence · 2020Article
- ART Adherence Among Men Who Have Sex with Men Living with HIV: Key Challenges and Opportunities.Current HIV/AIDS reports · 2020Review
- Influence of the First Consultation on Adherence to Antiretroviral Therapy for HIV-infected Patients.The open AIDS journal · 2016Article
- A Review of Recent Literature on Trauma Among Individuals Living with HIV.Current HIV/AIDS reports · 2015Article
- HIV Drug Therapy in the Americas 16-18 April 2015, Mexico City, Mexico.Journal of the International AIDS Society · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.
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