Evidence map›Paper›PMID 24410300›Full record

ReviewAIDS research and human retroviruses2014

Toward an endgame: finding and engaging people unaware of their HIV-1 infection in treatment and prevention.

David N Burns, Victor DeGruttola, Christopher D Pilcher, Mirjam Kretzschmar, Christopher M Gordon, Elizabeth H Flanagan, Christopher Duncombe, Myron S Cohen

Abstract readReview
In one paragraph

Review in AIDS research and human retroviruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Attomolar Detection of HIV-1 With Label-Free RCA-rCRISPR on Smartphone.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
  6. Late HIV diagnosis: trends, risk factors, and progress toward the 2025 target of <20% late diagnosis in 23 EU/EEA countries, 2022 to 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Maximizing the Efficiency of Active Case Finding for SARS-CoV-2 Using Bandit Algorithms.Medical decision making : an international journal of the Society for Medical Decision Making · 2021
    Article
  11. Article
  12. Observational
  13. Designing & Conducting Trials To Reliably Evaluate HIV Prevention Interventions.Statistical communications in infectious diseases · 2019
    Article
  14. Review
  15. Article
  16. Review
  17. An Adaptive Approach to Locating Mobile HIV Testing Services.Medical decision making : an international journal of the Society for Medical Decision Making · 2018
    Article
  18. mHealth · 2018
    Article
  19. A Flow-Based Model of the HIV Care Continuum in the United States.Journal of acquired immune deficiency syndromes (1999) · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David N Burns1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.
Victor DeGruttola
Christopher D Pilcher
Mirjam Kretzschmar
Christopher M Gordon
Elizabeth H Flanagan
Christopher Duncombe
Myron S Cohen

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 1988 to 2026
$93.6M
Methods to Advance the HIV Prevention Research AgendaR37AI051164 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI DEGRUTTOLA, VICTOR GERARD · 2012 to 2019
$3.3M
A Pilot of Intervention to Promote Acute HIV Testing by Ambulatory Care ProvidersR34MH096606 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PILCHER, CHRISTOPHER D · 2012 to 2014
$693k
NIAID NIH HHS P30 AI027763NIAID NIH HHS R37 AI051164NIMH NIH HHS R34 MH096606PHS HHS P30 A150410).PHS HHS R37 A151164
6 · The paper itself

Abstract

Epidemic modeling suggests that a major scale-up in HIV treatment could have a dramatic impact on HIV incidence. This has led both researchers and policymakers to set a goal of an "AIDS-Free Generation." One of the greatest obstacles to achieving this objective is the number of people with undiagnosed HIV infection. Despite recent innovations, new research strategies are needed to identify, engage, and successfully treat people who are unaware of their infection.

Indexed as

Health Services Needs and DemandAnti-HIV AgentsDisease Transmission, InfectiousHIV InfectionsHumansAnti-HIV Agents

Identifiers

PMID24410300
PMCPMC3938938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.