Evidence map›Paper›PMID 24409195›Full record

ArticlePersonalized medicine2013

Community pharmacists' attitudes towards clinical utility and ethical implications of pharmacogenetic testing.

Sony Tuteja, Kevin Haynes, Cara Zayac, Jon E Sprague, Barbara Bernhardt, Reed Pyeritz

Abstract read
In one paragraph

Article in Personalized medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. The Role of the Pediatric Pharmacist in Precision Medicine and Clinical Pharmacogenomics for Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026
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  16. An objective evaluation of fundamental pharmacogenomics knowledge among pharmacists and pharmacy students.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Article
  17. Article
  18. Article
  19. Pharmacists' Knowledge, and Insights in Implementing Pharmacogenomics in Saudi Arabia.International journal of environmental research and public health · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sony TutejaPenn Center for the Integration of Genetic Healthcare Technologies, PA, USA ; Perelman School of Medicine at the University of Pennsylvania, Division of Translational Medicine & Human Genetics, Smilow Translational Research Center, 3400 Civic Center Boulevard, Building 421, 11-142, PA 19104-5158, USA.
Kevin HaynesCenter for Clinical Epidemiology & Biostatistics, Perelman School of Medicine at the University of Pennsylvania, PA, USA.
Cara ZayacPenn Center for the Integration of Genetic Healthcare Technologies, PA, USA.
Jon E SpragueThe Raabe College of Pharmacy, Ohio Northern University, Ada, OH, USA.
Barbara BernhardtPenn Center for the Integration of Genetic Healthcare Technologies, PA, USA ; Perelman School of Medicine at the University of Pennsylvania, Division of Translational Medicine & Human Genetics, Smilow Translational Research Center, 3400 Civic Center Boulevard, Building 421, 11-142, PA 19104-5158, USA.
Reed PyeritzPenn Center for the Integration of Genetic Healthcare Technologies, PA, USA ; Perelman School of Medicine at the University of Pennsylvania, Division of Translational Medicine & Human Genetics, Smilow Translational Research Center, 3400 Civic Center Boulevard, Building 421, 11-142, PA 19104-5158, USA.

Funding

Penn Center for ELSI Research in Emerging Genetic Technologies in Health CareP50HG004487 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI PYERITZ, REED E · 2007 to 2012
$6.2M
NHGRI NIH HHS P50 HG004487
6 · The paper itself

Abstract

aimTo examine community pharmacists' attitudes towards pharmacogenetic (PGx) testing, including their views of the clinical utility of PGx and the ethical, social, legal and practical implications of PGx testing.

methodsA web-based survey administered to 5600 licensed community pharmacists in the states of Ohio and Pennsylvania (USA).

resultsOf 580 respondents, 78% had a Bachelor of Science degree in pharmacy and 58% worked in a chain drug store. Doctors of pharmacy-trained pharmacists had a significantly higher knowledge score than those with a Bachelor of Science in pharmacy (3.2 ± 0.9 vs 2.6 ± 0.6; p < 0.0001). All pharmacists had positive attitudes towards PGx and most (87%) felt it would decrease the number of adverse events, and optimize drug dosing. More than half (57%) of pharmacists felt that it was their role to counsel patients regarding PGx information. Many (65%) were concerned that PGx test results may be used to deny health insurance.

conclusionRegardless of the type of education, all pharmacists had positive attitudes towards PGx. There is still a concern among pharmacists that PGx test results may be used to deny health insurance and, thus, there is a need to educate pharmacists about legal protections prohibiting certain forms of unfair discrimination based on genotype.

Indexed as

community pharmacyethicsgenetic testingpersonalized medicinepharmacistspharmacogeneticspharmacogenomics

Identifiers

PMID24409195
PMCPMC3881266

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.