ArticleFrontiers in neuroanatomy2014
Perineuronal nets and GABAergic cells in the inferior colliculus of guinea pigs.
Article in Frontiers in neuroanatomy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Anatomical and neurochemical profiles of GABAergic projection neurons in the mouse inferior colliculus.Brain structure & function · 2025Article
- Age-related upregulation of perineuronal nets on inferior collicular cells that project to the cochlear nucleus.Frontiers in aging neuroscience · 2023Article
- Inferior collicular cells that project to the auditory thalamus are increasingly surrounded by perineuronal nets with age.Neurobiology of aging · 2021Article
- Perineuronal nets and subtypes of GABAergic cells differentiate auditory and multisensory nuclei in the intercollicular area of the midbrain.The Journal of comparative neurology · 2020Article
- Neuropeptide Y Expression Defines a Novel Class of GABAergic Projection Neuron in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- The Effect of Hapln4 Link Protein Deficiency on Extracellular Space Diffusion Parameters and Perineuronal Nets in the Auditory System During Aging.Neurochemical research · 2020Article
- The Density of Perineuronal Nets Increases With Age in the Inferior Colliculus in the Fischer Brown Norway Rat.Frontiers in aging neuroscience · 2020Article
- Subtypes of GABAergic cells in the inferior colliculus.Hearing research · 2019Review
- A novel class of inferior colliculus principal neurons labeled in vasoactive intestinal peptide-Cre mice.eLife · 2019Article
- Expression of aggrecan components in perineuronal nets in the mouse cerebral cortex.IBRO reports · 2018Article
- Perineuronal nets in subcortical auditory nuclei of four rodent species with differing hearing ranges.The Journal of comparative neurology · 2018Article
- Inhibitory Neural Circuits in the Mammalian Auditory Midbrain.Journal of experimental neuroscience · 2018Review
- Metabolomics and neuroanatomical evaluation of post-mortem changes in the hippocampus.Brain structure & function · 2017Article
- Weaving a Net of Neurobiological Mechanisms in Schizophrenia and Unraveling the Underlying Pathophysiology.Biological psychiatry · 2016Review
- Wisteria Floribunda Agglutinin-Labeled Perineuronal Nets in the Mouse Inferior Colliculus, Thalamic Reticular Nucleus and Auditory Cortex.Brain sciences · 2016Article
- Extracellular Molecular Markers and Soma Size of Inhibitory Neurons: Evidence for Four Subtypes of GABAergic Cells in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Organization of the Zone of Transition between the Pretectum and the Thalamus, with Emphasis on the Pretectothalamic Lamina.Frontiers in neuroanatomy · 2016Article
- Losing the sugar coating: potential impact of perineuronal net abnormalities on interneurons in schizophrenia.Schizophrenia research · 2015Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Perineuronal nets (PNs) are aggregates of extracellular matrix that have been associated with neuronal plasticity, critical periods, fast-spiking cells and protection from oxidative stress. Although PNs have been reported in the auditory system in several species, there is disagreement about the distribution of PNs within the inferior colliculus (IC), an important auditory hub in the midbrain. Furthermore, PNs in many brain areas are preferentially associated with GABAergic cells, but whether such an association exists in the IC has not been addressed. We used Wisteria floribunda agglutinin staining and immunohistochemistry in guinea pigs to examine PNs within the IC. PNs are present in all IC subdivisions and are densest in the central portions of the IC. Throughout the IC, PNs are preferentially associated with GABAergic cells. Not all GABAergic cells are surrounded by PNs, so the presence of PNs can be used to subdivide IC GABAergic cells into "netted" and "non-netted" categories. Finally, PNs in the IC, like those in other brain areas, display molecular heterogeneity that suggests a multitude of functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.