Evidence map›Paper›PMID 24408925›Full record

ArticleCancer research2014

Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors--letter.

David C Binder, Hans Schreiber

Abstract readLetterComment
In one paragraph

Article in Cancer research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Current position of TNF-α in melanomagenesis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Review
  7. Article
  8. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2014
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David C BinderAuthors' Affiliations: Committees on Cancer Biology and Immunology, and Department of Pathology, The University of Chicago, Chicago, Illinois.
Hans Schreiber
University of Chicago · US

Funding

Protein Expression and Peptide CoreP01CA097296 · NCI · UNIVERSITY OF CHICAGO · PI MEREDITH, STEPHEN C. · 2003 to 2012
$15.0M
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)T32HD007009 · NICHD · UNIVERSITY OF CHICAGO · PI NANCY B SCHWARTZ · 1985 to 2026
$13.0M
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007090 · NIAID · UNIVERSITY OF CHICAGO · PI Peter Aidan Savage · 1985 to 2026
$11.7M
PATHOBIOLOGY OF MYELOMA AND ANTI-IDIOTYPIC IMMUNITYR01CA022677 · NCI · UNIVERSITY OF CHICAGO · PI SCHREIBER, HANS · 1985 to 2024
$6.3M
IMMUNOLOGY OF UNIQUE TUMOR-SPECIFIC ANTIGENSR01CA037156 · NCI · UNIVERSITY OF CHICAGO · PI SCHREIBER, HANS · 1985 to 2017
$3.1M
"UNIQUE" TUMOR ANTIGENS RECOGNIZED BY CD8+ T CELLSP01CA074182 · NCI · UNIVERSITY OF CHICAGO · PI MEREDITH, STEPHEN C. · 1998 to 2001
$1.3M
NCI NIH HHS P01 CA074182NCI NIH HHS P01 CA097296NCI NIH HHS P01-CA97296NCI NIH HHS R01 CA022677NCI NIH HHS R01 CA037156NCI NIH HHS R01-CA22677NCI NIH HHS R01-CA37516NIAID NIH HHS T32 AI007090NICHD NIH HHS T32 HD007009NICHD NIH HHS T32 HD009007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCancer VaccinesCTLA-4 AntigenFemaleNeoplasms, ExperimentalProgrammed Cell Death 1 ReceptorT-LymphocytesCancer VaccinesCTLA-4 AntigenProgrammed Cell Death 1 Receptor

Identifiers

PMID24408925
PMCPMC3905982
OpenAlexW2118378412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.