ArticleMolecular biology and evolution2014
Genomic analyses of three malaria vectors reveals extensive shared polymorphism but contrasting population histories.
Article in Molecular biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Article
- Molecular characterization of potential Plasmodium-Blocking Serratia spp. bacteria in field-caught malaria mosquito in Burkina Faso.Parasites & vectors · 2025Article
- Ghost lineages can invalidate or even reverse findings regarding gene flow.PLoS biology · 2022Article
- Contemporary NMolecular ecology resources · 2021Article
- Coalescent Analysis of Phylogenomic Data Confidently Resolves the Species Relationships in the Anopheles gambiae Species Complex.Molecular biology and evolution · 2018Article
- Uncovering vector, parasite, blood meal and microbiome patterns from mixed-DNA specimens of the Chagas disease vector Triatoma dimidiata.PLoS neglected tropical diseases · 2018Article
- Reduced-representation sequencing identifies small effective population sizes of Anopheles gambiae in the north-western Lake Victoria basin, Uganda.Malaria journal · 2018Article
- Genome-wide analyses of the Bemisia tabaci species complex reveal contrasting patterns of admixture and complex demographic histories.PloS one · 2018Article
- Unravelling the Genetic Diversity among Cassava Bemisia tabaci Whiteflies Using NextRAD Sequencing.Genome biology and evolution · 2017Article
- malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication.PLoS medicine · 2017Review
- Genomic insights into adaptive divergence and speciation among malaria vectors of theEvolutionary applications · 2017Article
- Chromosome arm-specific patterns of polymorphism associated with chromosomal inversions in the major African malaria vector, Anopheles funestus.Molecular ecology · 2017Article
- TheeLife · 2017Article
- Pollutants and Insecticides Drive Local Adaptation in African Malaria Mosquitoes.Molecular biology and evolution · 2017Article
- Microgeographical structure in the major Neotropical malaria vector Anopheles darlingi using microsatellites and SNP markers.Parasites & vectors · 2017Article
- Chromosomal inversions and ecotypic differentiation in Anopheles gambiae: the perspective from whole-genome sequencing.Molecular ecology · 2016Article
- Genotyping of whole genome amplified reduced representation libraries reveals a cryptic population of Culicoides brevitarsis in the Northern Territory, Australia.BMC genomics · 2016Article
- The Genetic Basis of Host Preference and Resting Behavior in the Major African Malaria Vector, Anopheles arabiensis.PLoS genetics · 2016Article
- A genomic perspective on hybridization and speciation.Molecular ecology · 2016Review
- Genomic signatures of population decline in the malaria mosquito Anopheles gambiae.Malaria journal · 2016Article
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7 authors.
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Abstract
Anopheles gambiae s.l. are important malaria vectors, but little is known about their genomic variation in the wild. Here, we present inter- and intraspecies analysis of genome-wide RADseq data, in three Anopheles gambiae s.l. species collected from East Africa. The mosquitoes fall into three genotypic clusters representing described species (A. gambiae, A. arabiensis, and A. merus) with no evidence of cryptic breeding units. Anopheles merus is the most divergent of the three species, supporting a recent new phylogeny based on chromosomal inversions. Even though the species clusters are well separated, there is extensive shared polymorphism, particularly between A. gambiae and A. arabiensis. Divergence between A. gambiae and A. arabiensis does not vary across the autosomes but is higher in X-linked inversions than elsewhere on X or on the autosomes, consistent with the suggestion that this inversion (or a gene within it) is important in reproductive isolation between the species. The 2La/2L+(a) inversion shows no more evidence of introgression between A. gambiae and A. arabiensis than the rest of the autosomes. Population differentiation within A. gambiae and A. arabiensis is weak over approximately 190-270 km, implying no strong barriers to dispersal. Analysis of Tajima's D and the allele frequency spectrum is consistent with modest population increases in A. arabiensis and A. merus, but a more complex demographic history of expansion followed by contraction in A. gambiae. Although they are less than 200 km apart, the two A. gambiae populations show evidence of different demographic histories.
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