ArticleScience (New York, N.Y.)2014
Modular organization of axial microcircuits in zebrafish.
Article in Science (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed.
- Redefining the central pattern generator for vertebrate locomotion.Nature reviews. Neuroscience · 2026Review
- Time-dependent adaptations of damaged neurons and their microenvironment in the regenerating adult zebrafish spinal cord.Science advances · 2026Article
- Hoxa9 compensates for the absence of Hoxc9 in suppressing limb-type motor neurons in sharks.Zoological letters · 2026Article
- Voltage imaging in zebrafish using high-speed light-sheet microscopy.Neurophotonics · 2026Review
- The characteristics of cortical activation during gait in children with spastic diplegic cerebral palsy.Frontiers in pediatrics · 2026Article
- A novel behavioral paradigm using mice to study predictive postural control.Frontiers in neuroscience · 2026Article
- Oligodendrocytes support functional development of subcortical premotor neurons and navigation.bioRxiv : the preprint server for biology · 2025Article
- Article
- Neuronal Circuit Evolution: From Development to Structure and Adaptive Significance.Cold Spring Harbor perspectives in biology · 2025Review
- Development of the semicircular canals and otolithic organs of the vertebrate inner ear.Current topics in developmental biology · 2025Review
- Evolutionarily conserved brainstem architecture enables gravity-guided vertical navigation.PLoS biology · 2024Article
- Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis.bioRxiv : the preprint server for biology · 2024Article
- Electrical Synapses Mediate Embryonic Hyperactivity in a Zebrafish Model of Fragile X Syndrome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- A brainstem circuit for gravity-guided vertical navigation.bioRxiv : the preprint server for biology · 2024Article
- Molecular blueprints for spinal circuit modules controlling locomotor speed in zebrafish.Nature neuroscience · 2024Article
- Functional organization of vestibulospinal inputs responsible for tail postural control in larvalFrontiers in neurology · 2024Article
- Multisensory navigational strategies of hatchling fish for dispersal.Current biology : CB · 2023Article
- Organization of vestibular circuits for postural control in zebrafish.Current opinion in neurobiology · 2023Review
- Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS.Nature reviews. Neuroscience · 2023Review
- Spinal Interneurons: Diversity and Connectivity in Motor Control.Annual review of neuroscience · 2023Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Locomotion requires precise control of spinal networks. In tetrapods and bipeds, dynamic regulation of locomotion is simplified by the modular organization of spinal limb circuits, but it is not known whether their predecessors, fish axial circuits, are similarly organized. Here, we demonstrate that the larval zebrafish spinal cord contains distinct, parallel microcircuits for independent control of dorsal and ventral musculature on each side of the body. During normal swimming, dorsal and ventral microcircuits are equally active, but, during postural correction, fish differentially engage these microcircuits to generate torque for self-righting. These findings reveal greater complexity in the axial spinal networks responsible for swimming than previously recognized and suggest an early template of modular organization for more-complex locomotor circuits in later vertebrates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.