Evidence map›Paper›PMID 24408217›Full record

ArticleDatabase : the journal of biological databases and curation2014

DevMouse, the mouse developmental methylome database and analysis tools.

Hongbo Liu, Rangfei Zhu, Jie Lv, Hongjuan He, Lin Yang, Zhijun Huang, Jianzhong Su, Yan Zhang, Shihuan Yu, Qiong Wu

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hongbo LiuDepartment of Developmental Biology, School of Life Science and Technology, State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150001, China, Department of Computational Systems Biology, College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China, Department of Food Science, School of Food Science and Engineering, Harbin Institute of Technology, Harbin 150001, China and Department of Respiratory Medicine, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Rangfei Zhu
Jie Lv
Hongjuan He
Lin Yang
Zhijun Huang
Jianzhong Su
Yan Zhang
Shihuan Yu
Qiong Wu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation undergoes dynamic changes during mouse development and plays crucial roles in embryogenesis, cell-lineage determination and genomic imprinting. Bisulfite sequencing enables profiling of mouse developmental methylomes on an unprecedented scale; however, integrating and mining these data are challenges for experimental biologists. Therefore, we developed DevMouse, which focuses on the efficient storage of DNA methylomes in temporal order and quantitative analysis of methylation dynamics during mouse development. The latest release of DevMouse incorporates 32 normalized and temporally ordered methylomes across 15 developmental stages and related genome information. A flexible query engine is developed for acquisition of methylation profiles for genes, microRNAs, long non-coding RNAs and genomic intervals of interest across selected developmental stages. To facilitate in-depth mining of these profiles, DevMouse offers online analysis tools for the quantification of methylation variation, identification of differentially methylated genes, hierarchical clustering, gene function annotation and enrichment. Moreover, a configurable MethyBrowser is provided to view the base-resolution methylomes under a genomic context. In brief, DevMouse hosts comprehensive mouse developmental methylome data and provides online tools to explore the relationships of DNA methylation and development. Database URL: http://www.devmouse.org/

Indexed as

Databases, GeneticGenes, DevelopmentalSoftwareAnimalsDNA MethylationGenomicsHumansMiceSearch Engine

Identifiers

PMID24408217
PMCPMC3885893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.